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It has always bothered our field that rodent cortical bone is convenient to study but generally lacks Haversian organisation, a very clever adaptation by larger mammals. My team @SVIResearch took a deep dive into this. academic.oup.com/edrv/article/d…
academic.oup.com Preclinical Rodent Models for Human Bone Disease, Including a Focus on Cortical Bone Abstract. Preclinical models (typically ovariectomized rats and genetically altered mice) have underpinned much of what we know about skeletal biology. The 
