🧬 PD-L1: One Biomarker, Three Different Scores
Why can the same tumor be PD-L1-positive for one immunotherapy but negative for another?
🔹 TPS measures PD-L1 expression on tumor cells
🔹 CPS includes tumor cells and selected immune cells
🔹 IC measures the tumor area occupied by PD-L1-positive immune cells
💡 Different assays, scoring systems, and thresholds can influence immunotherapy selection. PD-L1 scores are not interchangeable.
The future may lie in combining PD-L1 testing with spatial immune profiling.
oncodaily.com/oncolibrary/im…
#Immunotherapy #OncoDailyIO
Why can the same tumor be PD-L1-positive for one immunotherapy but negative for another?
🔹 TPS measures PD-L1 expression on tumor cells
🔹 CPS includes tumor cells and selected immune cells
🔹 IC measures the tumor area occupied by PD-L1-positive immune cells
💡 Different assays, scoring systems, and thresholds can influence immunotherapy selection. PD-L1 scores are not interchangeable.
The future may lie in combining PD-L1 testing with spatial immune profiling.
oncodaily.com/oncolibrary/im…
#Immunotherapy #OncoDailyIO
