Liangyi Chen

What must a model know about cells to predict how a tissue responds to intervention?

Our preprint, VITAL: New Biology in the Age of AI, is now on Zenodo.

A proposed research programme, open for discussion:
doi.org/10.5281/zenodo…

1/5 From resolving live-cell structures to measuring functional differences.

Our preprint combines SIM-fdFLIM with ratio-preserving reconstruction (RIVE) for ~100 nm lifetime imaging.

We welcome live-cell collaborations.
biorxiv.org/content/10.648…

How do islet δ-cells shape hormone secretion?

On 6 Nov, I’ll host Patrik Rorsman at Peking University: “Pancreatic somatostatin secretion in health and disease.”

09:30–10:30 Beijing time | B117, Research Building No. 2
#Diabetes #IsletBiology

How will biology, physics, computing and engineering shape the next frontier?

Join Pavel Kabat, HFSPO Secretary-General, at Peking University:

“Life Science Frontiers in the 21st Century”
27 Oct 2026 | 09:00–10:00 Beijing time (UTC+8)
B117, College of Future Technology

COMET preprint: 3.75-g mesoscope. A 5-min recording captured calcium activity from 15,449 labeled L2/3 neurons across a broad dorsal-cortex field (up to 10 mm) in a freely moving mouse. From spine-level 2P and MIMAS to a measurement interface for VITAL.

biorxiv.org/content/10.648…