Overacre Lab

@OveracreLab

Pittsburgh, PA OveracreLab.com Joined April 2010

1.3K Following 1.6K Followers 2K Posts

Latest posts 5

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Overacre Lab @OveracreLab Oct 22

Very excited to share our latest paper, out today in Cell, led by @ItzDipyaman! This project started out with a curiosity as to how and why irAEs happen. Even more peculiar is that WT mice never develop irAEs…and why was that?

cell.com/cell/fulltext/…

www.cell.com Lifestyle-induced regulatory T cell fragility primes adverse events after immune checkpoint blockade Dietary and microbial alterations increase susceptibility to irAEs by promoting IFN-γ-driven Treg fragility and cytotoxic tissue-resident T cell responses. Treg-specific disruption of IFN-γ signaling...

Overacre Lab @OveracreLab 6d

Had a wonderful time sharing our latest work on diet, microbiome, and irAEs at @sitcancer this year! Amazing work by @ItzDipyaman and others in the lab and at @PittTweet and @UPMCHillmanCC

Overacre Lab @OveracreLab Nov 5

The SITC Microbiome Special Interest Group has officially launched! Join us at our first meetup at SITC Friday, Nov. 6 5:30-6pm at the SITC booth or signup online at sitcancer.org/get-involved/s…. @sitcancer #microbiome #immunotherapy

Overacre Lab @OveracreLab Oct 5

Proud of these two stellar PhD students for their awards at our recent departmental retreat! @Kate_Wolfgang_ @jessica_jana_

Overacre Lab @OveracreLab Oct 1

Celebrating our latest paper being accepted for publication! More details coming soon.