How does an mRNA become “cytoplasmic” after leaving the nucleus?
Our new preprint identifies PAIP1 as a factor that couples mRNA export to poly(A)-binding protein exchange, mRNP maturation, poly(A)-tail control, and early development.
biorxiv.org/content/10.648…
Our new preprint identifies PAIP1 as a factor that couples mRNA export to poly(A)-binding protein exchange, mRNP maturation, poly(A)-tail control, and early development.
biorxiv.org/content/10.648…
www.biorxiv.org PAIP1 couples mRNA export to cytoplasmic mRNP remodeling and poly(A) homeostasis Messenger ribonucleoproteins (mRNPs) acquire distinct protein compositions as they move from the nucleus to the cytoplasm, yet how this transition is coordinated and how inefficient remodeling... 