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De Camilli Lab
@PDClab
Laboratory of Pietro De Camilli - Department of Neuroscience at Yale University
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Bridge-like lipid transfer protein 3A (BLTP3A) is associated with membranes of the late endocytic pathway and is an effector of CASM biorxiv.org/content/10.110…
www.biorxiv.org Bridge-like lipid transfer protein 3A (BLTP3A) is associated with membranes of the late endocytic... Recent studies have identified a family of rod-shaped proteins which includes VPS13 and ATG2 and are thought to mediate unidirectional lipid transport at intracellular membrane contacts by a bridge... A complex of the lipid transport ER proteins TMEM24 and C2CD2 with band 4.1 at cell–cell contacts rupress.org/jcb/article/22…
rupress.org A complex of the lipid transport ER proteins TMEM24 and C2CD2 with band 4.1 at cell–cell contacts The ER-anchored lipid transfer protein TMEM24/C2CD2L and its paralog C2CD2 mediate the formation of ER–plasma membrane junctions at sites of cell–cell cont Overlapping role of synaptophysin and synaptogyrin family proteins in determining the small size of synaptic vesicles biorxiv.org/content/10.110…
www.biorxiv.org Overlapping role of synaptophysin and synaptogyrin family proteins in determining the small size of... Members of the synaptophysin and synaptogyrin family are vesicle proteins with four transmembrane domains. In spite of their abundance in synaptic vesicle (SV) membranes, their role remains elusive... Our new preprint reveals that the interaction of the bridge-like lipid transport protein VPS13A with the lipid scramblase XK at ER-plasma membrane contacts in K562 cells correlates with erythroid differentiation @ChaseAmos15 @YaleCellBio @YaleNeuro biorxiv.org/content/10.110…
www.biorxiv.org Erythroid differentiation dependent interaction of VPS13A with XK at the plasma membrane of K562... Mutations of the bridge-like lipid transport protein VPS13A and of the lipid scramblase XK result in Chorea Acanthocytosis (ChAc) and McLeod syndrome (MLS) respectively, two similar conditions...