Bladder washing from a 56 year old man with intermittent dysuria and papillary lesion in the bladder shows numerous dysplastic squamous cells. Which diagnostic category of the Paris System should be applied? #ParisSystem (see below photos and poll)
Paris System 2.0
@ParisSystem2
Official account for information regarding Paris System for Urinary Cytology version 2.0 | Supported by @cytopathology and @IACytology | curator @eva_wojcik
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Anyone has cytology images of this type of HGUC? We are looking for 🦓 @eva_wojcik @cytopathology @IACytology
Lipid-rich urothelial carcinoma. It is a rare and high grade variant with large lipoblast-like cells with cytoplasmic vacuoles indenting the nuclei.
#gupath #pathology #BladdercancerView quoted post on X
Excellent example - fibrovascular cores - no dx of LGUN without them!
@ParisSystem2 @eva_wojcik @barkanga @marcoslepe @twmarkc @pembeoltulu @PennPathLabMed @DiagnosticCyto @JASCJOURNAL @kriyer68 @sam_albadriView quoted post on X
About 25%of HGUC can have some degree of squamous differentiation - malignant sq cells in urine. Also, there is primary Sq cell ca of bladder - associated with Schistosomiasis and/or any chronic irritation ex stones
@dkurtycz @ParisSystem2 Can you briefly explain the image? Skin cancer in the bladder? I teach honors A&P and wish to show them this... but need help! Thank you!View quoted post on X
N/C > 0.7 – the paramount of #ParisSystem for dx of HGUC. What to do with case like this (see below photo)? N/C<0.7 due to degeneration. F/U biopsy positive for CIS. Should we call: (see poll)
