Powerhouse Biology

Do we dare use the word superhuman, and at the same time stay true to science?
Welcome to a new frontier of human biology: At Powerhouse Biology, we build capability therapeutics, medicines that add function to human cells. Stay tuned for October 12, when we share the 2026 White Paper "Engineered human resilience and durability".

Please add our 2026 White Paper "Engineered human resilience and durability" to your weekend reading list! 🧵

drive.google.com/file/d/1oBWJ4i…

We're making psychedelics*!

We design nature-inspired therapeutics and work to get them functioning inside human biology. With huge challenges ahead, and particularly in this automation + LLM era, we need human brains that are creative, connected, and on fire. This is us putting that into practice.

*said our Ebru (paper marbling) instructor.

Spotted in the wild: Powerhouse Biology's @rachel8407 hits our very first #JPM running at @cglifeagency's Sweat Equity 5K.

We are building a new therapeutic platform centered on mitochondrial control, arguably one of the most underexploited levers in age-related disease.

Find us tonight at @statnews @ #JPM26 to learn how we’re opening a new frontier in drug development.

@foresightinst's Vision Weekend kicked off at @altos_labs, partied at the @internetarchive on Saturday, and culminated at Lighthaven this Sunday. Boy do I love this community of future-ready gnerks. It's a place where you can think and talk freely about frontier tech.

At @Powerhouse_Bio, we have a deep focus on mitochondrial biology as a tractable entry point into a new therapeutic space: they're enclosed by two lipid bilayers, contain a heritable information carrier in the form of DNA, their biology is in a sense well studied because we can learn from prokaryote biology, and they're a subsystem that we can readily model computationally.

Amused to say that advancing the human species was definitely not the wildest item on the communal to-do list.