Markus J. Buehler

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@ProfBuehlerMIT

McAfee Professor of Engineering @MIT; Founder; AI-Driven Scientific Discovery

Cambridge, MA meche.mit.edu/people/faculty… Joined December 2014

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Markus J. Buehler @ProfBuehlerMIT Oct 29

We're one day away from our ScienceClaw Hackathon - see you all tomorrow afternoon Oct 30, 2026 at the @MIT @medialab for an exciting weekend.

Thank you to our sponsors @nvidia , @claudeai, @formlabs, @nebiusai, @EdisonSci, @Stifel Venture Banking, @Google, @romixbio, @askalphaxiv, the @MITEngineering, and @LilaSciences for supporting the event and providing resources for our teams. A dream team of leaders in agentic AI, AI for science, and scaling discovery!

And thank you to our amazing organizing team Habib Haddad, Calvin Chin, @e14fund, Andrea Porras, @fwang108_, @JaimeBerkovich, @SubhadeepPal, Bruno Howard, Awu Chen, Keira Boone, @leemmarom, and @maxwellbauer, and to our judges @evijit, Desiree Plata, Yilun Du, Riken Shah, Ian Ferguson, and @NikitaFedik for contributing their time and expertise.

We are also grateful to the broader community joining us from Hardmode, Sundai, Harvard University, the University of Michigan, MIT, and @ReactorfieldAI, bringing together expertise and perspectives across institutions and disciplines.

Looking forward to seeing what we build together!

1:14

Markus J. Buehler @ProfBuehlerMIT 5d

We’re hiring an Executive Director for the MIT AI Exchange - this is a great opportunity to help shape how MIT advances AI in research and learning, working with faculty and colleagues across the Institute to build programs, capabilities, and partnerships. Please share with anyone who might be interested and consider applying. Link in reply.

Markus J. Buehler @ProfBuehlerMIT 5d

Models improving and editing models directly in weight space - wild! Exciting work from my colleagues at MIT…opening interesting new possibilities

Rikiya Takehi @rikiyatakehi 5d

We asked GPT-6 Astra to edit Qwen3.5-0.8B weights to improve math.
It directly changed only 0.016% of weights, fixing 0.8B's reasoning loops & improving math up to 6x and even instruction following 3x, without gradients or training.

We call this Weight-Space Programming: frontier LLMs can now natively read/write neural network weights! 🧵
Blog: rikiyat.github.io/blog/weight-sp…

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Markus J. Buehler @ProfBuehlerMIT Oct 31

And...we're launched! We kicked off the ScienceClaw Hackathon with @e14fund yesterday - incredible energy in the room with people from all around the US and beyond pushing the interface of AI and science!

Thank you to our sponsors @nvidia @claudeai @openai @formlabs @nebiusai @EdisonSci @Stifel Venture Banking, @Google @romixbio @askalphaxiv @MITEngineering @LilaSciences @ReactorfieldAI Sundai and more

Markus J. Buehler Verified account @ProfBuehlerMIT Oct 29

We're one day away from our ScienceClaw Hackathon - see you all tomorrow afternoon Oct 30, 2026 at the @MIT @medialab for an exciting weekend.

Thank you to our sponsors @nvidia , @claudeai, @formlabs, @nebiusai, @EdisonSci, @Stifel Venture Banking, @Google, @romixbio, @askalphaxiv, the @MITEngineering, and @LilaSciences for supporting the event and providing resources for our teams. A dream team of leaders in agentic AI, AI for science, and scaling discovery!

And thank you to our amazing organizing team Habib Haddad, Calvin Chin, @e14fund, Andrea Porras, @fwang108_, @JaimeBerkovich, @SubhadeepPal, Bruno Howard, Awu Chen, Keira Boone, @leemmarom, and @maxwellbauer, and to our judges @evijit, Desiree Plata, Yilun Du, Riken Shah, Ian Ferguson, and @NikitaFedik for contributing their time and expertise.

We are also grateful to the broader community joining us from Hardmode, Sundai, Harvard University, the University of Michigan, MIT, and @ReactorfieldAI, bringing together expertise and perspectives across institutions and disciplines.

Looking forward to seeing what we build together!

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Markus J. Buehler @ProfBuehlerMIT Oct 29

Wonderful welcome to Cambridge, Massachusetts @ycombinator @agupta - let’s partner on some events if you’re up for it!

Ankit Gupta Verified account @agupta Oct 28

Cambridge has always been the best place in the world to be an academic researcher. These days, a lot of cutting edge research also happens in industry, and Cambridge is the home to many amazing research startups, spanning AI research, robotics, biotech, defense, and industrials.

We'd love for these two worlds to meet eachother, so we're bringing YC Paper Club to Cambridge!

if you're a researcher in industry or academia, request a spot below.
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