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RESOLUTE - Research Empowerment on Solute Carriers

@RESOLUTE_IMI

The RESOLUTE & REsolution IMI consortia aim at triggering an escalation in the intensity of research on Solute Carriers (SLCs) transporters worldwide.
This work has received support from the EU/EFPIA Innovative Medicines Initiative 2 Joint Undertaking (RESOLUTE grant No 777372). re-solute.eu Joined January 2019
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RESOLUTE - Research Empowerment on Solute Carriers @RESOLUTE_IMI
Check out this tour-de-force in technology and assay development by our partners at Novartis, @mpi_mr_hd, and @CeMM_News: dlvr.it/T7Vyjf
www.cell.com AspSnFR: A genetically encoded biosensor for real-time monitoring of aspartate in live cells Hellweg et al. introduce AspSnFR, a genetically encoded green fluorescent biosensor designed for the real-time measurement of aspartate concentrations in live cells. AspSnFR enables studies of amino...
Cell Chemical Biology @CellChemBiol May 28, 2024
Online now! AspSnFR: A genetically encoded biosensor for real-time monitoring of aspartate in live cells by Lars Hellweg, Kai Johnsson, @PLeippe, and colleagues at @EPFL_en @mpi_mr_hd @CeMM_News dlvr.it/T7Vyjf #chembiol
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RESOLUTE - Research Empowerment on Solute Carriers @RESOLUTE_IMI
Structural characterization of human urea transporters UT-A and UT-B and their inhibition | Science Advances science.org/doi/10.1126/sc…
www.science.org Structural characterization of human urea transporters UT-A and UT-B and their inhibition Crystal and cryo-EM structures of human urea transporters UT-A and UT-B enable structure-based design of selective inhibitors.
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RESOLUTE - Research Empowerment on Solute Carriers @RESOLUTE_IMI
We are out of words... We are grateful to our fantastic speakers, poster presenters, SAB members and participants, that joined us during the last @IHIEurope RESOLUTE conference in #Vienna. We are sure they will #CarryTheTorch for future research on molecular #transporters.
CeMM @CeMM_News Sep 29, 2023
On 27-29 September 2023, the @RESOLUTE_IMI & REsolution Final Conference took place in Vienna 🇦🇹! ~200 participants gathered to listen to top global #SLCs experts, learn more about the project's results & engage in meaningful scientific discussions! ➡️ bit.ly/46loPfs
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RESOLUTE - Research Empowerment on Solute Carriers @RESOLUTE_IMI
ABCC1 and glutathione metabolism limit the efficacy of BCL-2 inhibitors in acute myeloid leukemia
nature.com/articles/s4146…
www.nature.com ABCC1 and glutathione metabolism limit the efficacy of BCL-2 inhibitors in acute myeloid leukemia Nature Communications - BCL-2 inhibition using Venetoclax has emerged as a promising therapy in Acute Myeloid Leukaemia (AML), but primary and acquired resistance is a main limitation of this...