We got 2 big birds with one stone:
1) DeCAF-Pearl makes all-atom cofolding much faster than previously possible and 2) enables inference time search.⚡️
An incredible amount of work was done by a very talented team, and it was a pleasure to participate:)
1) DeCAF-Pearl makes all-atom cofolding much faster than previously possible and 2) enables inference time search.⚡️
An incredible amount of work was done by a very talented team, and it was a pleasure to participate:)
Protein–ligand cofolding models are getting incredibly powerful… but do they have to be so slow? 🧬🐢💊
Our new preprint introduces a new flow-map framework called DeCAF for fast few-step cofolding — up to 5× faster while preserving sample quality on the SOTA Pearl model and 20x faster than Boltz 1x. ⚡🧵
📜 Blog: genesis.ml/news/genesis-m…
🔗arXiv: arxiv.org/abs/2606.08375
Code (coming soon): github.com/genesistherape…View quoted post on X
