Rappsilber laboratory

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We’re thrilled to share that we’ve officially begun the My Green Lab Certification process! 📷 This marks an important step toward making our laboratory operations more sustainable and environmentally conscious.

The AlphaLink2 paper is now online! It’s joint work with @rbolab and @JorgStulke. AlphaLink2 integrates crosslinking MS data into AlphaFold-Multimer. AlphaLink2 really shines for challenging targets like antigen-antibody complexes. doi.org/10.1038/s41467…

We got an ERC synergy grant to work on and understand with Julia Mahamid (EMBL), Jan Kosinsky (EMBL), and Rachel Green (Johns Hopkins University, USA) ribosomes inside their cellular context and develop tools to study molecular processes inside cells at atomic resolution.

#AlphaLink2 goes #ColabFold 😎 @sokrypton #AlphaFold  biorxiv.org/content/10.110… colab.research.google.com/github/Rappsil…

In collaboration with the @rbolab, we are pleased to present AlphaLink2 - a modified version of AlphaFold-Multimer that is capable of directly incorporating experimental residue-residue contact data from crosslinking MS (and potentially other techniques as well). (1/7)