Tomorrow's vector technology! Cheers to the IU-Bloomington team and the GIVAX team for their amazing progress in using Rotavirus Platform Technology to create combination vaccines again rotavirus and other enteric pathogens.
PattonRotaLab
@RotavirusL
Rotahoosier molecular virologist, Training and advocating for my team of super scientists
876 Following 1.1K Followers 1.4K Posts
Latest posts 5
www.biorxiv.org Production of OSU G5P[7] Porcine Rotavirus Expressing a Fluorescent Reporter by Reverse Genetics Rotaviruses are a significant cause of severe, potentially life-threatening gastroenteritis in the young of many economically important animals. Although vaccines against porcine rotavirus exist,... 
journals.asm.org T7 expression plasmids for producing a recombinant human G1P[8] rotavirus comprising RIX4414... RV1 (Rotarix , GSK), the most widely used rotavirus vaccine, is formulated from the human G1P[8] virus RIX4414 (1, 2). To protect against rotavirus gastroenteritis, >24 million children received the... Terrific article by Asha Philip and Sannoong Hu demonstrating the use of rotavirus as a vector system for expressing glycosylated proteins. Recombinant Rotavirus Expressing the Glycosylated S1 Protein of SARS-CoV-2 biorxiv.org/content/10.110…
www.biorxiv.org Recombinant Rotavirus Expressing the Glycosylated S1 Protein of SARS-CoV-2 Reverse genetic systems have been used to introduce heterologous sequences into the rotavirus segmented double-stranded (ds)RNA genome, enabling the generation of recombinant viruses that express...