SCI member Paul Khavari & others found that p63 and FOXK1 work together to reshape DNA organization in squamous cell cancer, switching on cancer-promoting genes. This interaction was found in tumors, but not normal tissue. brnw.ch/21x6TEg
Steven Artandi, MD, PhD
@SCIDirector
Stanford University medical oncologist and cancer scientist, and Director of the Stanford Cancer Institute. Follows and retweets are not endorsements.
1.6K Following 4.1K Followers 1.8K Posts
Latest posts 5
SCI member @HaydenGephartMD & others report QBS72S reached cerebrospinal fluid and was well tolerated in #BreastCancer leptomeningeal disease, with some patients experiencing sustained disease stability or improvement. brnw.ch/21x6Qia
academic.oup.com Phase 2 test of QBS72S for breast cancer leptomeningeal disease AbstractBackground. Leptomeningeal disease (LMD) is a devastating complication of metastatic breast cancer that leads to severe neurologic symptoms and poo SCI leader Melissa Bondy & others found mental disorders were associated with higher cancer-specific mortality, with the strongest link 2–5 years after diagnosis. Findings support integrating mental health care into #CancerSurvivorship. brnw.ch/21x6Qi9
SCI member Ansuman Satpathy & others engineered synthetic transcription factors that reprogram #CARTCells to boost cancer-killing ability, reduce exhaustion, and improve persistence, potentially making cell therapies more effective against tumors. brnw.ch/21x6JCg
SCI member Michael Bassik & others mapped over 92 million enhancer-gene interactions across human cell types and tissues, improving our ability to link genetic variants to the genes they affect and understand the biology underlying disease. brnw.ch/21x6GdE
