Spidr Idp

@SPIDR_IDP

SPIDR project in Leeds and Oxford to elucidate roles of intrinsically disordered regions

Leeds, Oxford spidr-slola.com Joined January 2023

52 Following 40 Followers 44 Posts

Latest posts 5

Spidr Idp @SPIDR_IDP Nov 30, 2024

New understanding of a cancer relevant protein reveals opportunities for drug discovery birmingham.ac.uk/news/2024/new-…

www.birmingham.ac.uk New understanding of a cancer relevant protein reveals opportunities for drug discovery - Univers... A new approach to targeting a protein involved in cell division, which can misfunction in cancer, has revealed new insights into how it functions.

Spidr Idp @SPIDR_IDP Nov 29, 2024

Just out @ChemicalScience - the latest SPiDR publication features TACC3 peptidomimetics - these allosterically displace N-Myc and activate Aurora-A.
pubs.rsc.org/en/content/art…

pubs.rsc.org Constrained TACC3 peptidomimetics for a non-canonical protein–protein interface elucidate alloste... Peptidomimetic design for non-canonical interfaces is less well established than for α-helix and β-strand mediated protein–protein interactions. Using the

Spidr Idp @SPIDR_IDP Sep 29, 2024

New @SPIDR_IDP project from @baylisslab @richard_bayliss @JRHCellCycle revealing the role of CEP192 in regulating Aurora A. embopress.org/doi/full/10.10…

Spidr Idp @SPIDR_IDP Sep 13, 2024

Super sessions at the cell cycle kinases meeting organised by our very own @richard_bayliss @baylisslab @MWrightLab and Jenny Miles in Leeds this afternoon.

Spidr Idp @SPIDR_IDP Sep 11, 2024

Check out this new collaborative SPiDR preprint with
@MWrightLab, @baylisslab and @AJWilsonGroup. Constrained TACC3 peptidomimetics for a non-canonical protein-protein interface elucidate allosteric communication in Aurora-A Kinase | ChemRxiv - go.shr.lc/47ohUDY

chemrxiv.org Constrained TACC3 peptidomimetics for a non-canonical protein-protein interface elucidate alloste... Peptidomimetic design for non-canonical interfaces is less well established than for α-helix and β-strand mediated protein-protein interactions. Using the TACC3/Aurora-A kinase interaction as a...