Sam Orange

I'm excited to share our latest work showing that exercise rapidly triggers molecular changes in the blood that act directly on colon cancer cells to remodel gene expression and promote DNA damage repair

Full text: onlinelibrary.wiley.com/doi/10.1002/ij…

BBC coverage:
bbc.co.uk/news/articles/…

We're seeking expertise in supportive/sports bras for exercising after breast surgery. This will be paid consultancy work (0.5-1 day). If you have the expertise & are interested, please email sam.orange@newcastle.ac.uk.

New preprint:
Exercise-conditioned serum enhances double strand break repair, upregulates DNA repair gene PNKP, and induces transcriptional changes that reflect increased mitochondrial metabolism and reduced proliferation in colon cancer cells.

biorxiv.org/cgi/content/sh…

Can anyone access the full-text for this paper please?

The V˙E/V˙co2 Slope During Maximal Treadmill Cardiopulmonary Exercise Testing: REFERENCE STANDARDS FROM FRIEND
pubmed.ncbi.nlm.nih.gov/33470730/

sam.orange@newcastle.ac.uk - thank you

Standing room only at today's workshop!

26 women with breast cancer worked together to agree what exercise instructors need to know when delivering physical activity programmes to women during and after treatment.

This is part of our ongoing research: breastcancernow.org/our-research/r…