Simon Fandler-Höfler

@SimonFaHo

Neurologist focussing on intracerebral haemorrhage, stroke and neurological emergency medicine @MedUniGraz, Austria and @UCLStrokeRes

Graz Joined June 2023

136 Following 187 Followers 83 Posts

Latest posts 5

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Simon Fandler-Höfler @SimonFaHo Nov 3, 2024

(1/3) In which patients with intracerebral hemorrhage should advanced work-up such as digital subtraction angiography be performed? The MACRO score may help - using a few simple MRI parameters it allows to reliably assess the risk of macrovascular causes: neurology.org/doi/10.1212/WN…

www.neurology.org MRI-Based Prediction of Macrovascular Causes of Intracerebral Hemorrhage | Neurology Background and ObjectivesAlthough most spontaneous intracerebral hemorrhages (ICHs) are due to cerebral small vessel diseases (SVDs), between 1 in 7 and 1 in 10 are due to a macrovascular cause....

Simon Fandler-Höfler @SimonFaHo Nov 29, 2025

Should patients with AF and history of ICH be treated with oral anticoagulation? A subanalysis of PRESTIGE-AF underlines individualised decisions (based on neuroimaging) - particular risk of recurrent ICH when cortical superficial siderosis and chronic ICH on MRI are present.

Neurology Journal @GreenJournal Nov 27, 2025

In this study the authors assessed the role of neuroimaging in identifying patients with particular susceptibility to #IschemicStroke or intracerebral hemorrhage, with the potential to enable individualized risk stratification: hubs.la/Q03V_lDq0

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Simon Fandler-Höfler @SimonFaHo Nov 10, 2025

1/3 Should patients with AF and history of intracerebral haemorrhage treated with oral anticoagulation? This subanalysis of PRESTIGE-AF provides new data, indicating that individualised decisions based on neuroimaging (+clinical profiles) might be prudent: neurology.org/doi/10.1212/WN…

www.neurology.org Neuroimaging Markers Associated With Recurrent Stroke in Intracerebral Hemorrhage and Atrial... Background and ObjectivesAnticoagulation in patients with intracerebral hemorrhage (ICH) and atrial fibrillation reduces the risk of ischemic stroke (IS), but also potentially causes an excess risk...

Simon Fandler-Höfler @SimonFaHo Feb 19, 2025

1/4 Iatrogenic cerebral amyloid angiopathy (iCAA) is a scary rare disease affecting patients 30-50 years after possible CNS exposure to pathological amyloid-beta. In a large international collaboration, we investigated neuroimaging findings and clinical outcomes in 51 patients.

Simon Fandler-Höfler @SimonFaHo Oct 16, 2024

In a large analysis of >20000 patients with stroke, men had a higher rate of cerebral microbleeds and lacunes (corrected for co-factors), but women had more severe white matter hyperintensities. Are there sex differences in the pathophysiology of cerebral small vessel disease?

JAMA Network Open @JAMANetworkOpen Oct 15, 2024

In this pooled patient data analysis of >20k patients with strokes, women had lower prevalence of cerebral microbleeds and lacunes, but more severe white matter hyperintensities, suggesting sex-related differences in cerebral small vessel disease. ja.ma/3BUqTkp
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