Mount Sinai Genetics

@SinaiGenetics

We are shaping the future of genomic research, medicine, and education in the largest, most diverse healthcare system in New York City. 🧬 #genetics #genomics

New York, NY flowcode.com/page/sinaigene… Joined February 2018

414 Following 1.6K Followers 1.3K Posts

Latest posts 5

Mount Sinai Genetics @SinaiGenetics Oct 28

Parkinson’s symptoms began before age 50 in 4 of 11 people with type 1 Gaucher disease and Parkinson’s in a Mount Sinai study. The authors recommend screening from age 40 to support earlier recognition. pmc.ncbi.nlm.nih.gov/articles/PMC13… #GaucherDisease #Parkinsons

Research highlight titled Gaucher disease and Parkinson’s, recognizing early symptoms, with a conceptual cyan folded-paper brain. Larger text describes a retrospective comparison of 11 people with type 1 Gaucher disease and Parkinson’s and 21 matched Gaucher controls. Systemic Gaucher biomarkers did not clearly distinguish the groups. Parkinson’s symptoms began before age 50 in four of the 11 cases. The authors recommend Parkinson’s screening from age 40. A caveat states that this was a small study at one center and screening benefits were not tested. All seven authors are credited, including equal first authors Ayuko Iverson and Drew B. Sinha. Published in Molecular Genetics and Metabolism Reports in 2026. Artwork is conceptual, not study data.

Mount Sinai Genetics @SinaiGenetics Oct 1

A new Mount Sinai study in Neuron links genetic ancestry and DNA structure in the tau gene region to differences in gene expression and tau RNA forms. These patterns vary by brain region and cell type. cell.com/neuron/fulltex… #Alzheimers #AlzheimersResearch #Genomics @SinaiBrain

Mount Sinai publication highlight for a Neuron study. Headline: New DNA subtype identified in the tau gene region. H1_A is more common in people of African ancestry. Scientific takeaway: Relying on one genetic marker can misclassify this region, complicating studies of neurodegenerative disease risk. An original conceptual neuron illustration has a cell body, connected branching dendrites and a long axon with terminal branches; it is not study data. Credits: Sarah A. Weitzman; Alison M. Goate, DPhil; Chiara Pedicone, PhD; and colleagues. Published online September 29, 2026. DOI: 10.1016/j.neuron.2026.09.008.

Mount Sinai Genetics @SinaiGenetics Sep 21

This #PostdocAppreciationWeek, we’re shining a light on our #postdocs and their contributions to genetics & genomic science. Your dedication, curiosity, mentorship and collaboration move our work forward every day. We appreciate you year-round. This week, we celebrate you. #NPAW

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Mount Sinai Genetics @SinaiGenetics Sep 17

A Mount Sinai-led study conducted with @wearecbtn, CPTAC, the Philadelphia Coalition for a Cure and other collaborators identifies candidate treatment targets for high-grade #glioma and age- and sex-related differences in tumor biology: mountsinai.org/about/newsroom… #Proteogenomics

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Mount Sinai Genetics @SinaiGenetics Jul 20

Single-cell atlases guide biology and train AI, but who is represented?

A study led by Kuan-lin Huang analyzed >13,500 samples: European ancestry was overrepresented, while Asian, African and Latino individuals were underrepresented.

Read more: mountsinai.org/about/newsroom…