A comb with electrified teeth regrew nearly all lost hair on balding skin in a month.
The device, called Detangle, was built by engineers at Beihang University in Beijing and described in Nature Communications. Its teeth carry tiny electrodes set at different heights, plus little pods of medicine, so that each stroke creates an electric field reaching about nine times deeper into the hair follicles than electrodes placed on the skin.
That field gently stimulates the follicles and briefly opens up their cells, letting the comb slip in two treatments: a gene that makes a growth factor called VEGF-A, which builds new blood vessels, and a molecule that silences the enzyme that makes DHT, the hormone that shrinks follicles in pattern baldness.
Mice with this type of hair loss were combed once every three days, and after a month the bald patches regrew nearly 100% of their hair.
Pattern baldness is the most common form of hair loss, and today's options have drawbacks. Pills that block DHT can cause side effects throughout the body, while creams like minoxidil struggle to reach deep enough into the scalp to work well for everyone. A comb that delivers treatment right to the follicle during an ordinary daily habit would sidestep both problems.
That said, every result so far comes from mice whose baldness was induced in the lab, and human scalps and hormones may respond differently.
source: Liu, F., Yao, F., Sun, H., et al. (2026). Combing-triggered electrostimulation synchronizing deep delivery for rapid hair regrowth in androgenetic alopecia. Nature Communications.
The device, called Detangle, was built by engineers at Beihang University in Beijing and described in Nature Communications. Its teeth carry tiny electrodes set at different heights, plus little pods of medicine, so that each stroke creates an electric field reaching about nine times deeper into the hair follicles than electrodes placed on the skin.
That field gently stimulates the follicles and briefly opens up their cells, letting the comb slip in two treatments: a gene that makes a growth factor called VEGF-A, which builds new blood vessels, and a molecule that silences the enzyme that makes DHT, the hormone that shrinks follicles in pattern baldness.
Mice with this type of hair loss were combed once every three days, and after a month the bald patches regrew nearly 100% of their hair.
Pattern baldness is the most common form of hair loss, and today's options have drawbacks. Pills that block DHT can cause side effects throughout the body, while creams like minoxidil struggle to reach deep enough into the scalp to work well for everyone. A comb that delivers treatment right to the follicle during an ordinary daily habit would sidestep both problems.
That said, every result so far comes from mice whose baldness was induced in the lab, and human scalps and hormones may respond differently.
source: Liu, F., Yao, F., Sun, H., et al. (2026). Combing-triggered electrostimulation synchronizing deep delivery for rapid hair regrowth in androgenetic alopecia. Nature Communications.