Luciano Sposato 🇦🇷🇨🇦

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@SposatoL

Stroke Neurologist
• 𝗛𝗲𝗮𝗱 Stroke Program @WesternU
• 𝗦𝗲𝗰𝘁𝗶𝗼𝗻 𝗘𝗱𝗶𝘁𝗼𝗿 Neurocardiology @StrokeAHA_ASA
• 𝗖𝗵𝗮𝗶𝗿 @WorldStrokeOrg H&B TaskForce

London, Ontario bit.ly/LS_BIO Joined February 2009

2.2K Following 5.4K Followers 3.5K Posts

Latest posts 5

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Luciano Sposato 🇦🇷🇨🇦 @SposatoL May 25, 2025

What if I told you it is possible to increase 6⃣ times the detection of cardioaortic thrombi in stroke patients with a simple tweak to your current workflow?
🤯🤯🤯
We would only need to screen 1⃣4⃣ patients to find 1⃣ thrombus! Curious? Read on! DAYLIGHT Trial
sciencedirect.com/science/articl…
#Stroke #Cardiology #MedTwitter #Neurocardiology #Neurology
Read till the end for a surprise
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Luciano Sposato 🇦🇷🇨🇦 @SposatoL Sep 26, 2025

If you are coming to the World
Stroke Congress, don’t miss the Pre-Congress on October 21!
Hands-on Simulation at Val d’Hebron.

World Stroke Org @WorldStrokeOrg Sep 26, 2025

🚨Pre-Congress Workshop Announcement: as part of the 17th World Stroke Congress in #Barcelona (October 22–24), we are excited to invite you to a hands-on Acute Stroke Simulation

🧠 Enhancing Acute Stroke Response Across the Continuum of Care
📍 Vall d’Hebron University Hospital, Barcelona, Spain
📅 Tuesday, October 21, 2025
⏰ 13:00 – 18:00

This interactive session will provide participants with practical training to optimize acute stroke care and streamline response strategies across different stages of treatment.

👉Coordinated by two leading experts in the field:

- Prof. Octavio Marques Pontes-Neto Pontes, USP - Universidade de São Paulo
- Dr. Carlos Molina, Head of Stroke Center, Hospital Universitari Vall d'Hebron

Don’t miss the opportunity to strengthen your expertise ahead of the congress!

🔗 Learn more & register: worldstrokecongress.org/registration/?…

#StrokeEducation #StrokeSimulation #StrokeCare

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Luciano Sposato 🇦🇷🇨🇦 @SposatoL Sep 12, 2025

🧠✨ Looking forward to the World Stroke Congress 2025 in Barcelona (22–24 October)!

We have curated an exceptional program with global leading experts.

Don’t miss out, register now 🔗 worldstrokecongress.org/registration/ invt.io/1txbmg0zkam

#WSC2025 #StrokeCare #StrokeCongress

Luciano Sposato 🇦🇷🇨🇦 @SposatoL Sep 4, 2025

𝗪𝗼𝗿𝗹𝗱 𝗦𝘁𝗿𝗼𝗸𝗲 𝗖𝗼𝗻𝗴𝗿𝗲𝘀𝘀 𝟮𝟬𝟮𝟱
🎥 𝗪𝗮𝘁𝗰𝗵 𝘁𝗵𝗲 𝗳𝘂𝗹𝗹 𝘃𝗶𝗱𝗲𝗼 𝗯𝗲𝗹𝗼𝘄: Cutting-edge stroke science. No kidding!
Looking forward to seeing you all in 𝗕𝗮𝗿𝗰𝗲𝗹𝗼𝗻𝗮!
𝗥𝗲𝗴𝗶𝘀𝘁𝗲𝗿 𝘁𝗼𝗱𝗮𝘆.

#WSC2025 #Stroke #StrokeCongress #Neurotwitter #Cardiotwitter
@ShadiYaghi2 @InterNeurona @MicheleRomoli @WorldStrokeEd
@sheilambrasil @neurona_critica @Ash_Shoamanesh

World Stroke Org @WorldStrokeOrg Sep 2, 2025

⏰Only 1 month left - take advantage of the reduced registration fees and join us in Barcelona in October!

The opportunity to witness the most anticipated meeting in the field of stroke at the best possible rates is slipping away. Join thousands of stroke care specialists, reserve your spot among the foremost experts, and advance your career forward.
📅Regular Registration Deadline: September 30, 2025
🔗Register: worldstrokecongress.org/registration/

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Luciano Sposato 🇦🇷🇨🇦 @SposatoL Jul 19, 2025

🧠 Great paper on BNP and timing of AFDAS diagnosis
🔖Ref 1

📌 374 #stroke pt w/o known #Afib, but AFDAS detected on cardiac monitoring (BIOSIGNAL & GRAZ cohorts)

📉 Inhospital AFDAS (72%):
🧪 NT-proBNP at admission predicts in-hospital AFDAS
▪️Cutoff: 505 pg/mL → AUC 0.83
▪️OR = 5.4 | NPV = 96%
▪️Inhospital AFDAS: ↑ MACE & CV death

📉 Post-discharge AFDAS (28%)
🧪 Weak NT-proBNP signal

🔍 𝗜𝗠𝗣𝗢𝗥𝗧𝗔𝗡𝗖𝗘:
✅ Aligns with the 2024 EHJ framework:
▪️ Late AFDAS often ↓ burden, ↓er stroke risk
Fig 1, 🔖Ref 2

✅ Phenotypic mapping:
▪️Most inpatient AFDAS→ likely Type A
▪️Most post-discharge AFDAS → likely Type B
Fig 2, 🔖Ref 3

✅ Timing + biomarkers = phenotype
▪️Mirrors B2ADRISK-AFDAS model
⚠️ AFDAS phenotypes evolve over time
Fig 3, 🔖Ref 3

🔗 Ref 1: doi.org/10.1161/STROKE…
🔗 Ref 2: doi.org/10.1093/eurhea…
🔗 Ref 3: thelancet.com/article/PIIS14…