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Stainier Lab

@StainierLab

Our lab studies #development #regeneration #geneticrobustness @mpi_hlr. The account is run by various lab members.
Bad Nauheim mpi-hlr.de/104638/lab-mem… Joined March 2022
87 Following 2K Followers 177 Posts

Latest posts 5

Stainier Lab @StainierLab
Congratulations to Samuel Capon and coauthors on their latest study that dives into the fascinating world of phenotypic variation in Fibronectin mutants, exploring why the exact same mutation leads to different viability during embryonic development ! 🥳🎉 journals.plos.org/plosgenetics/a…
journals.plos.org A genetic modifier links integrin α5 to the phenotypic variation in fibronectin 1a mutant zebrafish Author summary Recent studies have identified apparently healthy individuals with mutations that would be expected to lead to disease. Why these individuals are disease resistant is not understood....
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Stainier Lab @StainierLab
Congratulations to the team! 🎉
Huge thanks to @ACHSEeV, the Köhler Foundation, and our brilliant team @StainierLab @MPI_HLR.

Science is a team effort, and this award recognizes that shared dedication.
More here 👉 mpi-hlr.de/391963/news_pu…
#RareDisease #EvaLuiseKöhler #Duchenne #DMD #TranscriptionalAdaptation
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Stainier Lab @StainierLab
Congratulations to @TJ_ThomasJuan and all the coauthors! 🎉
Thomas Juan @TJ_ThomasJuan Feb 28, 2025
Very proud to share my latest research on a novel biotechnological tool: The first use of a self-cleaving ribozyme to knock down an endogenous gene in a vertebrate model.

Thanks to the @StainierLab and to my co-authors #PLOSGenetics: dx.plos.org/10.1371/journa…
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Stainier Lab @StainierLab
Paper alert! Congrats to Lara, @CMDooley77, @DouglasAdamoski and @TJ_ThomasJuan for their great work on identifying the first example of Transcriptional Adaption in humans!🎉
5/5 🌟 Why It Matters:
First evidence of TA in humans! This work rethinks DMD treatment, showing mRNA decay itself can drive genetic compensation. Kudos to 1st Lara! @DouglasAdamoski @TJ_ThomasJuan & team! @MPI_HLR 🎉 #RareDisease
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