Steyn Lab

@SteynTBLab

We study #Mycobacterium #tuberculosis #Immunometabolism #Gasotransmitters #Bioenergetics #LungImaging #HostDirectedTherapies
@AHRI_News & @UABMicrobiology

Birmingham, USA., Durban, SA. scholars.uab.edu/display/asteyn Joined June 2022

89 Following 387 Followers 43 Posts

Latest posts 5

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Steyn Lab @SteynTBLab Apr 21

🫁 The GRR-HTB is a collaborative platform of @UABMicrobiology pathologists & scientists dedicated to transforming how TB is studied.

We aim to accelerate global TB research through access to human TB tissue samples and advanced analytical services 🧵 1/3

Steyn Lab @SteynTBLab Apr 23, 2025

🚨Exciting news!🚨We’ve launched the Global Research Resource for Human Tuberculosis, offering access to and analysis of human TB tissue, bridging the gap between basic science and clinical relevance
Visit us now! sites.uab.edu/tbresearchreso… #TBResearch #GlobalHealth #MedicalResearch

Steyn Lab @SteynTBLab Nov 18, 2024

frontiersin.org/journals/immun…

www.frontiersin.org Frontiers | Longitudinal mitochondrial bioenergetic signatures of blood monocytes and lymphocytes... The impact of human pulmonary tuberculosis (TB) on the bioenergetic metabolism of circulating immune cells remains elusive, as does the resolution of these e...

Steyn Lab @SteynTBLab Jul 19, 2024

🚨Published @eBioMedicine A new approach to study #Mtb physiology & #TB diagnosis. Our study uses #RNAscope to detect #Mycobacterium #tuberculosis mRNA in human tissue, even when traditional ZN staining fails. @UABMicrobiology @AHRI_News @UABPathology thelancet.com/journals/ebiom…

Steyn Lab @SteynTBLab Oct 6, 2023

New @SteynTBLab preprint🚨: Our team used #RNAscope to detect #Mycobacterium #tuberculosis mRNA and distinct #Mtb bacilli within the pathological spectrum of #TB lesions. We propose #RNAscope as a novel tool for #TB diagnosis and therapy. Congrats, all. biorxiv.org/content/10.110…
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Steyn Lab @SteynTBLab Oct 6, 2023

New @SteynTBLab preprint🚨: Our team used #RNAscope to detect #Mycobacterium #tuberculosis mRNA and distinct #Mtb bacilli within the pathological spectrum of #TB lesions. We propose #RNAscope as a novel tool for #TB diagnosis and therapy. Congrats, all. biorxiv.org/content/10.110…

www.biorxiv.org Detection of Mycobacterium tuberculosis in human tissue via RNA in situ hybridization Rationale Accurate TB diagnosis is hampered by the variable efficacy of the widely-used Ziehl-Neelsen (ZN) staining method to identify Mycobacterium tuberculosis ( Mtb ) acid-fast bacilli (AFB)....