Excited to share our recent PNAS paper (led by @Dani_B1256): pnas.org/doi/10.1073/pn…, where we discovered the mechanisms governing myelin integrity during the onset of myelination. We are grateful to collaborate with Ellisman lab (UCSD), @WertLaboratory, and UTSW EM Core (1/6).
Lu Sun
@SunLab19
Assistant Professor at UT Southwestern Medical Center studying how glial cells sculpt the nervous system. Views are my own.
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Glad to share our published version: “ Genetic targeting of premyelinating oligodendrocytes reveals activity-dependent myelination mechanisms”, led by @AksheevB
nature.com/articles/s4159…
nature.com/articles/s4159…
Excited to share the preprint led by Aksheev, a super talented postdoc in lab, in tackling the most mysterious stage during oligodendrogenesis and myelination: the premyelinating oligodendrocytes (1/n).
New preprint out from Sun Lab @SunLab19 We generated new premyelinating oligodendrocyte specific Cre mouse line and show that preOLs can remain immature for upto 8days in vivo. These immature cells can also respond to changes in neuronal activity. (1/2)View quoted post on X
Thanks for supporting our work! Image credit goes to @AksheevB who created new mouse lines to lineage trace newly formed oligodendrocytes in health and disease.
Visualizing cells in the mouse brain is helping scientists at @SunLab19 discover what drives neurodegenerative diseases like #Alzheimers and #ParkinsonsView quoted post on X
#ParkinsonsAwarenessMonth
We are grateful for the support from @klingensteinorg @UTSWBrain @UTSWNews @UTSWMolBiol that allows us to create new reagents and methods to tackle important questions in the field. This recognition goes to my amazing crew members.
OBI Investigator, Lu Sun, Ph.D., was awarded a 2023 Klingenstein-Simons Fellowship in Neuroscience. The award supports Dr. Sun's research into the roles of axons in #myelination. The award is given to highly promising early career scientists. Learn more: bit.ly/3Q3W81zView quoted post on X