@TaeWanKim0
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www.cell.com TNF-NF-κB-p53 axis restricts in vivo survival of hPSC-derived dopamine neurons Transient TNF-α inhibition overcomes a p53-dependent program that restricts the survival of grafted dopamine neurons and offers a clinically relevant strategy to enhance survival and promote functi... Providing a new protocol for applications in cell therapy for #ParkinsonsDisease: doi.org/10.1172/JCI190…
Tae Wan Kim @TaeWanKim0 et al. @MSKCancerCenter introduce a refined method for producing dopamine neurons in vitro. The Boost+ differentiation protocol adds FGF18 and IWP2 treatment at the neurogenesis stage, improving yield, neuron subtype identity, and locomotor function in implanted rats.
The figure shows expression of midbrain dopamine neuronal markers FOXA2, TH, and EN1 in day 60 neurons.View quoted post on X
www.linkedin.com 🎓DGIST Tenure-Track Faculty Position Opening 2025🎓 DGIST, with the world-class research environ... 🎓DGIST Tenure-Track Faculty Position Opening 2025🎓 DGIST, with the world-class research environment and highly talented students, is seeking exceptional faculty members to join our mission.... 