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Tate_Lab

@Tate_Lab

The Viral Immunity and Immunopathology Laboratory at
@Hudson_Research
@CiiiD_Research

Host-directed therapies for #influenza and pulmonary inflammation
Melbourne, Australia hudson.org.au/research-group… Joined March 2023
128 Following 108 Followers 45 Posts

Latest posts 5

Tate_Lab @Tate_Lab
🫁 It’s the epithelium, not myeloid cells.

Epithelial NLRP3 drives lung injury and fibrosis via IL‑18 and pro‑fibrotic neutrophils.

doi.org/10.1186/s12989…
link.springer.com Epithelial NLRP3 drives silica-induced lung injury and fibrosis through IL-18 and pro-fibrotic... Particle and Fibre Toxicology - Silicosis is a progressive inflammatory and fibrotic lung disease with no effective treatments beyond symptom management. While global NLRP3 inflammasome deficiency...
Tate_Lab @Tate_Lab
Excited to share our new work in @MucosalImmunol on preventing the #1 killer after flu: secondary bacterial pneumonia
mucosalimmunology.org/article/S1933-…
www.mucosalimmunology.org Short-course intranasal LAT9997 therapy limits post-influenza bacterial pneumonia by recalibrating... Influenza A virus (IAV) infection remains a major global health threat, not only due to its direct impact but also its role in predisposing the respiratory tract to secondary bacterial infections.1...
Tate_Lab @Tate_Lab
Our latest study is online - a novel host-directed therapy for influenza.
@CiiiD_Hudson @Hudson_Research academic.oup.com/jid/article/do…
academic.oup.com Harnessing Endogenous Peptide Compounds as Potential Therapeutics for Severe Influenza AbstractBackground. Excessive pulmonary inflammation and damage are characteristic features of severe influenza virus infections. LAT8881 is a synthetic 16
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