Taylor Research Group

@Taylorlab_Chem

Synthetic chemistry and chemical biology research group at the University of Arizona.

The University of Arizona taylorresearchgroup.org Joined October 2019

485 Following 755 Followers 123 Posts

Latest posts 5

Taylor Research Group @Taylorlab_Chem Nov 21, 2024

Check out the final version of our pyridinium-ylide alkylation manuscript on accessing highly bespoke pyridinium salts in @JOC_OL. Congrats to @Akash_Mamon and former REU student Ben! pubs.acs.org/doi/10.1021/ac…

pubs.acs.org A Pyridinium Ylide-Alkylation Strategy for the Structural Diversification of N‑Carbamoylpyridinium... Abstract. A pyridinium ylide-alkylation strategy has been developed for selectively accessing N,N-disubstituted pyridinium salts from monosubstituted pyrid

Taylor Research Group @Taylorlab_Chem Sep 27, 2024

Interested in getting your chemistry/biochemistry Ph.D. from a dynamic, multidisciplinary, and welcoming department? Then our program @uarizona @Biochem_Chem may be just for you! Am also excited to announce that all application fees are waived this year!

Taylor Research Group @Taylorlab_Chem Jun 4, 2024

Happy to share our latest preprint on @ChemRxiv expanding the chemical space surrounding our chembio pyridinium probes using ylide chemistry. Great for complex pyridiniums with sensitive functionality. Great work by @Akash_Mamon and former REU student Ben! chemrxiv.org/engage/chemrxi…

Taylor Research Group @Taylorlab_Chem Apr 30, 2024

Check out our latest preprint on @ChemRxiv in which we harness non-covalent interactions to direct site-selectivity in biomolecule acylation. Great work by coauthors @kuehl_nicholas , Hieu, and Joe! chemrxiv.org/engage/chemrxi…

Taylor Research Group @Taylorlab_Chem Oct 11, 2023

Our radical photocage work is out in @JACS! The photocage directly releases free CF3 radicals and enables MS-mapping of proteins w/ 1s rxns and prep-scale peptide trifluoromethylation in minutes. Impressive solo student author effort by @kuehl_nicholas! pubs.acs.org/doi/10.1021/ja…

pubs.acs.org Rapid Biomolecular Trifluoromethylation Using Cationic Aromatic Sulfonate Esters as Visible-Light... Abstract. Described here is a photodecaging approach to radical trifluoromethylation of biomolecules. This was accomplished by designing a quinolinium sulf