Wittrup Lab
@TheWittrupLab
The Wittrup lab at the @kochinstitute @MIT. Protein engineering for cancer immunotherapy. Run by lab members @MITChemE @MITdeptofBE
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Latest posts 5
Curious what we’ve been up to recently? Check out our posters at #SITC23 today to learn about collagen anchored cytokine therapy in canines (1094) and how Tregs constrain responses to collagen anchored anti-4-1BB agonist antibody therapy (1224)!
acir.org New insights on the mechanism of action of anti-CTLA-4 immune checkpoint blockade The mechanism of action of anti-CTLA-4 therapy remains incompletely understood. Hypotheses suggest that either antagonism of CTLA-4:B7 binding or Fc effector-mediated regulatory T cell (Treg)... Check out our latest work on the role Tregs play in limiting responses to local anti-4-1BB therapy. Also if you’re looking to hire post docs to study T cell biology/dysfunction Joseph is graduating soon and looking for positions!!
Excited to share my first first author paper and a large part of my PhD work. A quick tweetorial 🧵 (1/13)View quoted post on X
biorxiv.org/content/10.110…
Huge congrats to Dr. Anthony Tabet on a phenomenal PhD defense today.
Anthony was co-advised by the @AnikeevaLab and leveraged the unique skill sets of both labs to push the boundaries of cancer neuroimmunology. Excited to see what you accomplish next!
Anthony was co-advised by the @AnikeevaLab and leveraged the unique skill sets of both labs to push the boundaries of cancer neuroimmunology. Excited to see what you accomplish next!