Theodoris Lab

Happy to share a protocol for discovery of candidate therapeutic targets with Geneformer by @YujieZh1729!

Nature Protocols link: rdcu.be/ffApo
Google Colab: tinyurl.com/geneformertuto…

Really enjoyed talking with science journalist Andrew Han about art and science on his new podcast, Ion Genomics! Check it out here: iongenomics.bio/p/podcast-epis…

Excited to share MaxToki, a temporal AI model that predicts the impact of perturbations on cell states over time along dynamic trajectories. We applied MaxToki to predict how cells age across the human lifespan & discovered new cardiac pro-aging drivers that we validated in vivo.

Congrats to @hanimal725 and @madhavanvvs for their work in Nature Computational Science that demonstrated scaling laws for foundation models for network biology and implemented a quantization approach to enable resource-efficient predictions! rdcu.be/famFk

We are excited to share work led by @hanimal725 and @madhavanvvs developing a quantized multitask learning strategy for network biology, built on a foundation model pretrained on ~95M single-cell transcriptomes.

Manuscript: tinyurl.com/qmtl-gf
Model: huggingface.co/ctheodoris/Gen…