Thomas Berg

When biology pushes back
HBsAg suppression works but #HDV biology is more complex than expected. ALT flares with siRNA monotherapy suggest that cure may require targeting HBV/HDV ecosystem, not just one viral dependency
DOI: 10.1016/j.jhep.2026.06.040 @JHepatology #LiverTwitter

Tumor matrix is more than scaffold: collagen and collagen-fibronectin network architecture determines liver cancer cell stiffness and invasiveness, a new physical perspective #ECM #LiverCancer #LIVERTWITTER @EASLnews doi.org/10.1007/s13402…

Sex and the #Liver - Sex-related variations in liver homeostasis and disease: From zonation dynamics to clinical implications. doi: 10.1016/j.jhep.2025.08.007 #LiverTwitter @JHepatology @EASLnews #LiverCancer @CancerInflam @AASLDTweets #PathTwitter

🩸 New data add to current evidence on #PlasmaExchange in ACLF:
TPE may improve short-term survival in selected patients unresponsive
☞ More work needed to define who benefits & when #LiverTwitter #EASL #INASL #EFCLIF
jcehepatology.com/article/S0973-…

Standardizing HBcrAg overrange dilution improves early treatment monitoring in CHB
👉 FCS outperforms manufacturer’s diluent in accuracy & quality
Two-site validation with clinical implications
📄 doi.org/10.1016/j.viro…
#LiverTwitter @EASLnews @SaSi_Lens @Aelsharkawy75 @ICE_HBV