Timothy Gottschalk

@TimGottschalk

Lecturer, Monash Unit Dept Immunol. | Honorary Postdoc, Cell Death and Inflammatory Signalling, Hudson Institute | All posts are my own

Melbourne, Australia linkedin.com/in/timothygott… Joined August 2012

125 Following 156 Followers 94 Posts

Latest posts 5

Pinned post

Timothy Gottschalk @TimGottschalk Nov 12, 2024

Check out our new paper from the @_KateLawlor lab showing distinct roles for #necroptosis effectors RIPK3 (+ Caspase-8) that drives inflammation, and MLKL which regulates lipid handling in obesity-induced #MAFLD. @LSAjournal @CiiiD_Hudson @Hudson_Research life-science-alliance.org/content/8/1/e2…

www.life-science-alliance.org Divergent roles of RIPK3 and MLKL in high-fat diet–induced obesity and MAFLD in mice Cell death frequently occurs in the pathogenesis of obesity and metabolic dysfunction–associated fatty liver disease (MAFLD). However, the exact contribution of core cell death machinery to disease...

Timothy Gottschalk @TimGottschalk Oct 20, 2025

Check out our new study published in @ScienceAdvances from @HibbsLab @MonashImmunol led by Dr. Elan L'Estrange demonstrating a kinase-independent role for Lyn in restricting TLR activation and IFN I responses in autoimmune disease. science.org/doi/10.1126/sc…

www.science.org Lyn restrains lupus via kinase-independent mechanisms that limit Toll-like receptor activation and... Lyn restrains lupus by kinase-independent mechanisms that curb Toll-like receptor signaling and interferon responsiveness.

Timothy Gottschalk @TimGottschalk May 2, 2025

So proud that our fantastic study led by @Amy_Hsu_ from the @HibbsLab @MonashImmunol demonstrating the link between HCK activity and IL-17-mediated inflammatory lung disease driven by niche-filling unconventional T cells is out now in @eBioMedicine! doi.org/10.1016/j.ebio…

Timothy Gottschalk @TimGottschalk Dec 10, 2024

If you have a sec, check out our new paper by @Amy_Hsu_ with @HibbsLab (@MonashImmunol) and @ivana_hal (@imgprague) showing that CD53 drives cellular infiltration and inflammation in allergic airway asthma-like disease in @AllergyEaaci (it's a quick read). doi.org/10.1111/all.16…

onlinelibrary.wiley.com Tetraspanin CD53 Promotes Inflammation but Restrains Mucus Production in a Mouse Model of Allergic... Click on the article title to read more.

Timothy Gottschalk @TimGottschalk Jul 2, 2024

Take a look at our new review from @HibbsLab @MonashImmunol by our PhD student Elan L’Estrange-Stranieri on the dualistic role of Lyn kinase in immune cell signalling and involvement in lupus just published in @FrontImmunol! frontiersin.org/journals/immun…

www.frontiersin.org Frontiers | The dualistic role of Lyn tyrosine kinase in immune cell signaling: implications for... Systemic lupus erythematosus (SLE, lupus) is a debilitating, multisystem autoimmune disease that can affect any organ in the body. The disease is characteriz...