UEGJ

🧬 #PNPLA3 is a major genetic driver of #MASLD severity

🔸Linked to higher ALT/AST & liver stiffness
🔸Homozygous carriers had 2.57× higher risk of stiffness ≥9.1 kPa
🔸HSD17B13 lowered liver injury markers but not fibrosis risk

📖 #OpenAccess 👉 bit.ly/48sszie

🧪 #IgA deficiency complicates #CoeliacDisease diagnosis

🔸Present in 1.4–4.8% of coeliac disease
🔸Duodenal biopsy confirms diagnosis
🔸IgG antibodies decline slowly on a gluten-free diet

📖 #OpenAccess 👉 bit.ly/3V4a6W7

@my_ueg

🧭 #AcutePancreatitis is linked to long-term multisystem risks

🔸250 incident comorbidities over 13.7 yrs
🔸Key pathways involved digestive, metabolic, cardiopulmonary & mental health disorders
🔸All-cause mortality was 62% higher

📖 #OpenAccess 👉 bit.ly/4dYvTou

🧬Cirrhosis limits immune recovery after #HepatitisC cure

🔸HCV causes T-cell depletion
🔸T-cell recovery occurs mainly without fibrosis
🔸Cirrhosis leads to persistent lymphopenia & inflammatory dysregulation despite viral cure

📖 #OpenAccess 👉 bit.ly/4jM8SZP

🤖AI improves detection & reporting of colonic angiodysplasia

🔸Detection: 94.5% accuracy, 84.4% sensitivity
🔸LLM reporting check: 95.8% accuracy
🔸AI detected 23 cases vs 5 physician-reported

📖 #OpenAccess 👉 bit.ly/4ikUFjW

@my_ueg