UKY Center for Muscle Biology

@UKYCMB

The mission of the Center for Muscle Biology is to support excellence in basic and clinical research in the field of muscle biology.

Kentucky, USA uky.edu/chs/muscle Joined December 2017

121 Following 718 Followers 249 Posts

Latest posts 5

UKY Center for Muscle Biology @UKYCMB Jul 26, 2023

Exciting new study led by Jordan Fuqua of the Miller Lab, in collaboration with our CMB colleague, Dr. Dupont-Versteegden, found impaired proteostatic mechanisms responsible for the limited recovery of old skeletal muscle following atrophy
pubmed.ncbi.nlm.nih.gov/37448295/

pubmed.ncbi.nlm.nih.gov Impaired proteostatic mechanisms other than decreased protein synthesis limit old skeletal muscle... Our data suggest that the failure of old muscle to recover after disuse is not due to limitations in the ability to synthesize myofibrillar proteins but because of other impaired proteostatic...

UKY Center for Muscle Biology @UKYCMB Mar 11, 2023

An exciting new study led by Drs. Ismaeel and Van Pelt of the Dupont-Versteegden lab of the CMB.
nam04.safelinks.protection.outlook.com/?url=https%3A%…

UKY Center for Muscle Biology @UKYCMB Feb 8, 2023

Exciting new study from the Dupont-Versteegden lab led by Dr. Zachary Hettinger of the CMB.
physoc.onlinelibrary.wiley.com/doi/10.14814/p…

physoc.onlinelibrary.wiley.com The transcript interactome of skeletal muscle RNA binding protein motif 3 (RBM3) Skeletal muscle RNA binding protein motif 3 (RBM3) has been recognized as a potential regulator of muscle size, while potential mechanisms are unknown. This study isolates and characterizes the...

UKY Center for Muscle Biology @UKYCMB Dec 22, 2022

Fantastic new study pubmed.ncbi.nlm.nih.gov/36544018/
extending earlier work by the Peterson lab led by Dr. Cory Dungan
pubmed.ncbi.nlm.nih.gov/34904366/

pubmed.ncbi.nlm.nih.gov Senescence atlas reveals an aged-like inflamed niche that blunts muscle regeneration - PubMed Tissue regeneration requires coordination between resident stem cells and local niche cells1,2. Here we identify that senescent cells are integral components of the skeletal muscle regenerative niche...

UKY Center for Muscle Biology @UKYCMB Oct 5, 2022

nam04.safelinks.protection.outlook.com/?url=https%3A%…
Findings from TELEX Clinical Trial published in JAMA!! CMB colleagues, Drs. Kosmac & Peterson, members of the research team. 6-month telmisartan treatment did not improve 6-minute walk distance of PAD patients. Muscle data presented at upcoming at AHA conf

jamanetwork.com Effect of Telmisartan on Walking Performance in Patients With Lower Extremity Peripheral Artery... This randomized clinical trial compares the effect of telmisartan on 6-minute walk distance compared with placebo in patients with lower extremity peripheral artery disease at 6-month follow-up.