URSAchem

@URSAchemlab

Org Chemistry lab focused on asymmetric catalysis and medicinal chemistry at @IRBBarcelona. Professors Antoni Riera and Xavier Verdaguer. Student run account.

Barcelona ursa.cat Joined June 2016

203 Following 293 Followers 211 Posts

Latest posts 5

URSAchem @URSAchemlab Aug 3

Have you ever heard of phosphinitos?

In our latest work, we show that P*-stereogenic phosphinitos can serve as powerful ligands in asymmetric catalysis. We look forward to seeing what else these ligands can achieve!

Congrats to @martichickpea and team!

advanced.onlinelibrary.wiley.com/doi/10.1002/ad…

advanced.onlinelibrary.wiley.com Synergistic Mechanism Between Ir–Phosphinito Catalyst and HFIP Enables Asymmetric Hydrogenation of... A cooperative mechanism between a phosphinito Ir complex and HFIP provides a low-energy pathway for hydrogen activation. This allowed the development of a highly efficient catalytic system for the...

URSAchem @URSAchemlab May 28, 2025

Another fascinating year of demonstrations by our group at the IRB Barcelona Open Day. Great to reach out to the community and show off the excitment of chemistry! Many thanks to @IRBBarcelona for organising this fantastic event.

URSAchem @URSAchemlab Apr 14, 2025

Our PhD student, Sergi Rafael presented his thesis, Heterobifunctional Molecules: PROTACS and beyond.

From overcoming degrader resistance to rewiring ERF activity, Sergi discussed his work with fantastic animations. Congratulations Dr. Rafael!!

URSAchem @URSAchemlab Feb 6, 2025

Congrats to our PhD graduate Dr. Marina Bellido (@marinabellidom) and PhD student Marti Sidro (@martichickpea) for their recent work in developing the p-stereogenic phosphane ligand, MAdPHOS, which provides outstanding enantioselectivities in asymmetric hydrogenation of enamides!

Marina Bellido @marinabellidom Feb 1, 2025

Check out our latest work in @JOC_OL where we prepare a novel P-stereogenic phosphane ligand named MAdPHOS at @URSAchemlab together with @helsoleav and @martichickpea
pubs.acs.org/doi/abs/10.102…

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URSAchem @URSAchemlab Dec 20, 2024

Check out our work preparing 3,3-diarylallyl phthalimides as single diastereomers. we use this approach to synthesise various cyclopropylamines and achieve their highest enantioselectivities reported to date!

pubs.acs.org/doi/full/10.10…

Congrats to Martí Sidro (@Maarti164 ) et al!

pubs.acs.org Highly Enantioselective Synthesis of 3,3-Diarylpropyl Amines and 4‑Aryl Tetrahydroquinolines via... Abstract. Chiral nitrogen-containing compounds are crucial for the chemical, pharmaceutical, and agrochemical industries. Nevertheless, the synthesis of ce