Whetstine Lab

@WhetstineLab

Passionate Cancer Researcher and Science Advocate
FYI: John writes the tweets & they reflect his own opinions

whetstinelab.com Joined June 2015

667 Following 1.1K Followers 8.1K Posts

Latest posts 5

Pinned post

Whetstine Lab @WhetstineLab May 8, 2025

Amazing moment to share with my Mom! Amazing woman, advocate, survivor and person! Thrilled to co-lead our @FoxChaseCancer team @LUNGFORCE walk on Saturday at the Philadelphia Zoo.
A proud son, Cancer Researcher, & Director @CeiFccc - it is an honor!
cbsnews.com/philadelphia/v…

www.cbsnews.com 2025 Lung Force Walk is personal for mother and her son, a Fox Chase Cancer Center researcher Dr. Johnathan Whetstine is the director of the Cancer Epigenetics Institute at the Fox Chase Cancer Center and has received multiple Lung Cancer Discovery Awards. He and his mother, Jeane Whetstine,...

Whetstine Lab @WhetstineLab 6d

In case couldn't access the manuscript we had go advanced online on October 2 about #Epigenetic Factors Causing & Regulating #MYC #ecDNA and integrated #amplification - @NIH funded & public version available.

Scheduled Dec issue @MolecularCell

@CeiFccc

pmc.ncbi.nlm.nih.gov/articles/PMC13…

pmc.ncbi.nlm.nih.gov An Epigenetic Program Dictates MYC Amplification Dynamics that Promote Transient, Extrachromosomal... MYC amplification is common and often extrachromosomal (ecDNA) in cancer. In order to define how MYC DNA copy gains arises from diploid genomes, we assessed whether epigenetic enzymes directly...

Whetstine Lab @WhetstineLab Oct 6

@CeiFccc @FoxChaseCancer is Hiring #Epigenetics Faculty. Please share with anyone interested.

A dynamic group that appreciates mechanism & builds partneships across our center to also translate basic findings to clinical impact. A great place to be.

jobs.sciencecareers.org/job/680492/fac…

jobs.sciencecareers.org Faculty -Cancer Epigenetics Institute and Nuclear Dynamics and Cancer Program - Philadelphia,... The Fox Chase Cancer Center invites applicants for tenure-track faculty positions at the level of assistant professor and associate professor

Whetstine Lab @WhetstineLab Oct 2

How does MYC go from 2 copies to an amplified oncogene? 🧬🔬

Our New pub now @MolecularCell investigating how #epigenetic regulation controls genesis & progression of #MYC amplifications
@brkthroughprize
@NIH @CeiFccc

cell.com/molecular-cell…

@nytimes
nytimes.com/2026/10/02/sci…

www.cell.com An epigenetic program dictates MYC amplification dynamics that promote transient, extrachromosomal,... Ferman et al. demonstrate that epigenetic imbalance directly controls MYC oncogene amplification dynamics, which identifies possible biomarkers and therapeutic targets for aggressive tumors. When a...

Whetstine Lab @WhetstineLab Sep 23

My favorite Seminar Series! We host the #NEXTepiGEN series monthly @CeiFccc that highlight the brightest future faculty leaders in epigenetics, chromatin, DNA-dependent biology, and gene regulation, etc.

Hosted Dr. Sarah Hainer from Univ of Pittsburgh. Amazing science!