Yang Liu

According to idecRxiv, around 10% of iDEC projects over the past 6 years have gone on to peer-reviewed publication! Some project ideas have also been explored and published by other research groups.

The quality of this year’s student research was just as impressive! I’ve loved spending time with iDEC participants throughout the competition.

When we talk with AI researchers, one question comes up most frequently: do you have datasets focused on mutations at key protein positions?

Until now, building libraries for that usually meant a lot of DNA synthesis. We developed HGT-DGR as a faster and cheaper way to make them.
biorxiv.org/content/10.648…

Excited to share this work—we’ve been waiting a long time for it.

The searchable sequence space of DGR evolution is defined by its template (TR). However, fully exploring this space requires the TR sequence and DGR activity to remain stable over extended evolution—a major challenge in a continuously evolving population.

In E. coli, we solved this problem by coupling DGR with bacterial conjugation.

biorxiv.org/content/10.648…

A little DIY for Cambridge South’s opening day. Acknowledgement: AI helped with the design — and with code to scan and print the pieces.

Honored to be invited by Dr Xianghua “Cici” Li to attend Dr Grzegorz Kudla’s talk at KCL. I learned so much and left truly inspired! And a happy birthday to Ronnie!
@XianghuaLi2