Murphy Lab

www.nature.com Two-stage binding of mitochondrial ferredoxin-2 to the core iron-sulfur cluster assembly complex Nature Communications - De novo [2Fe-2S] cluster synthesis by the mitochondrial ISC complex requires electrons from ferredoxin-2 (FDX2). The authors map FDX2 binding to the core ISC complex,...

Murphy Lab @_Murphy_Lab · Feb 23, 2024

🎉 Our latest preprint is now online 👉 biorxiv.org/content/10.110…
Congrats to @RalfSteinhilper who determined #cryoEM structures of the ferredoxin 2-bound core iron-sulfur cluster assembly complex under reducing and turnover conditions at 2 Å resolution.

More below! 👇

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Murphy Lab @_Murphy_Lab · Jan 19, 2024

Happy to announce that our efforts to establish elemental mapping for cryo-EM ❄️ by EELS 🌈 are now shared on bioRxiv: biorxiv.org/content/10.110…
Congratulations to @zoliviapg and co-authors!

But wait - Can we map elements in 3D?
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www.nature.com Structural and mechanistic insights into Streptococcus pneumoniae NADPH oxidase Nature Structural & Molecular Biology - Using cryo-electron microscopy, the authors obtained structures of Streptococcus pneumoniae nicotinamide adenine dinucleotide phosphate (NADPH) oxidase...

Murphy Lab @_Murphy_Lab · Oct 20, 2023

Excited to share our preprint: “Structural and mechanistic insights into Streptococcus pneumoniae NADPH oxidase” in which we obtained a structure of a 46-kDa membrane protein to 2.2 Å resolution without fiducials.
tinyurl.com/zycuw3p6

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