David Hackett

@_davidhackett

Musgrave PhD scholar in @Surgery_TCD funded by @BreakthroCancer |🔬 microRNA as a therapeutic target in pancreatic cancer | BSc. Pharmacology graduate UCD

Joined September 2022

384 Following 258 Followers 351 Posts

Latest posts 5

David Hackett @_davidhackett Oct 29, 2025

Last week in Boston 🇺🇸, I was delighted to present my work on how microRNA-31-driven alterations in ATOX1 promote chemosensitivity in #PDAC at the @AACR/@theNCI/@EORTC International Conference on Molecular Targets and Cancer Therapeutics.
#PancreaticCancer #Targets25

David Hackett @_davidhackett Oct 24, 2025

Delighted to present my work at @AACR-@theNCI-@EORTC Intl Conference on Molecular Targets and Cancer Therapeutics in Boston. If you’re at the conference, please stop by my poster tomorrow (C100) to chat about miR-31/ATOX1 targeting in #PDAC #Targets25

aacrjournals.org/mct/article/24…

aacrjournals.org Abstract C100: Therapeutic targeting of microRNA-31 promotes chemosensitivity via ATOX1 in pancre... AbstractIntroduction:. Pancreatic ductal adenocarcinoma (PDAC) has a dismal long-term patient survival rate. This poor prognosis is due in part to poor patient responses to current standard-of-care...

David Hackett @_davidhackett Oct 2, 2025

Had a great time volunteering at the @BreakthroCancer Revolution Exhibition in Stephen’s Green Shopping Centre today! Loved @DeasyPamela’s inspiring story—every journey is unique, and this exhibition captures it. Definitely worth a visit!

Free tickets at cancerrevolution.ie

David Hackett @_davidhackett May 5, 2025

Exciting to see amifostine repurposed as a radioprotective agent for pancreatic cancer! Traditionally administered intravenously, a targeted nasal delivery method delivers it directly to the duodenum, where it shields healthy cells from radiation. Now entering clinical trials.

Anirban Maitra @Aiims1742 May 5, 2025

A novel modality for #PancreaticCancer therapy on the cover of @RiceUniversity magazine. The subject of radioprotection was near & dear to Cullen Taniguchi’s heart. I am glad to see progress on this @RiceUniversity - @MDAndersonNews collaboration!
magazine.rice.edu/spring-2025/br…

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David Hackett @_davidhackett Apr 4, 2025

Really enjoyed sharing my recent PhD findings on miR-31 as a regulator of radiosensitivity in pancreatic cancer, through its targeting of ATOX1 and GPx8 antioxidant activity, at the annual @irrsoc meeting 2025. Fantastic talks over the past two days!