Engineering a protein homodimer from a heterodimer. Proteins are cool. doi.org/10.1002/pro.70…
onlinelibrary.wiley.com Engineering a protein homodimer from a heterodimer: A chimeric DBHS protein Drosophila behavior/human splicing (DBHS) proteins are involved at nearly every stage of the RNA lifecycle. There are three paralogues in mammals—SFPQ, NONO and PSPC1—which form both homodimer and... Andrew C Marshall
@acmarshallphd
structural biology | condensed protein | University of Western Australia, @CharlieBondXray lab, @SMS_UWA
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Merry Christmas from our favourite sticky nucleic acid binding protein. Great work from @KoningHeidar @CharlieBondXray and team!
@NAR_Open
Structural plasticity of the coiled–coil interactions in human SFPQ academic.oup.com/nar/article/do…
@NAR_Open
Structural plasticity of the coiled–coil interactions in human SFPQ academic.oup.com/nar/article/do…
Hello @ausynchrotron. It's been a while! Can't wait to shoot some proteins with some X-rays on Wednesday #bioSAXS
Describing the different effects that the disordered parts of #SFPQ have on it's ability to form #condensates inside and outside the cell. Big thanks to Mihwa Lee @CharlieBondXray @AFox_Perth @HymanLab @AnggonoLab members for your input 🙏 #phaseseparation doi.org/10.1016/j.jmb.…
Thanks @CallumVerdonk for kicking off an interesting discussion on history and present state of science @PerthProteins #PPG2023