Discovery of Guanfacine as a Novel TAAR1 Agonist: A Combination Strategy through Molecular Modeling Studies and Biological Assays mdpi.com/2568246 #mdpipharmaceuticals via @MDPIOpenAccess
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Nice review on GPCR intracellualr allosteric modulator sites. Brian Krumme's NTSR1 structure (PDB 8FNO) was used but his paper was not cited (pubmed.ncbi.nlm.nih.gov/36917754/).
Pharmacologically targeting intracellular allosteric sites of GPCRs for drug discovery pubmed.ncbi.nlm.nih.gov/37852356/
Pharmacologically targeting intracellular allosteric sites of GPCRs for drug discovery pubmed.ncbi.nlm.nih.gov/37852356/