Ai Ing Lim

@AiingLim

Immunologist, Assistant Professor @PrincetonMolBio

Princeton, NJ limmunity.com Joined April 2016

570 Following 777 Followers 247 Posts

Latest posts 5

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Ai Ing Lim @AiingLim May 13

LIMmunity 2nd brew !!
Motherhood comes with superpower: pathogen protection!

nature.com/articles/s4158…

We often think moms are immunologically vulnerable to tolerate the baby. But I always wondered: why would evolution make such a critical period of life so dangerous?

www.nature.com Eosinophils drive intestinal remodelling and innate defence in reproduction Nature - From pregnancy until lactation, eosinophils accumulate in the small intestine where they regulate goblet cell fate and enhance innate defences against enteric pathogens.

Ai Ing Lim @AiingLim May 13

Really enjoyed reading this! Thank you so much for highlighting our work and for the thoughtful, constructive feedback that helped strengthen our study!!

Sing Sing Way @babiesresearch May 13

Protective maternal gut instincts nature.com/articles/d4158… So thankful to @nature for the opportunity to highlight with @jiahuisunsun another exciting example of immunology learned from mothers, “protective maternal gut instincts” by @aiinglim @princetonmolbio
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Ai Ing Lim @AiingLim May 13

Really enjoyed reading this. Thank you so much for highlighting our work and for the thoughtful, constructive feedback that helped strengthen the study!!

Sing Sing Way @babiesresearch May 13

Protective maternal gut instincts nature.com/articles/d4158… So thankful to @nature for the opportunity to highlight with @jiahuisunsun another exciting example of immunology learned from mothers, “protective maternal gut instincts” by @aiinglim @princetonmolbio
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Ai Ing Lim @AiingLim May 11

We found maternal helminths promote antiviral immunity in offspring! 🪱🤱

cell.com/cell-host-micr…

Don't worry! We are not suggesting reinfect everyone with worms! We found the metabolite, IPA, that enhances antiviral immunity!

www.cell.com Maternal helminths rewire the microbiota to promote offspring antiviral immunity Fernandes et al. show that maternal helminths, long-standing mammalian partners, confer antiviral immunity to offspring via the microbiota-derived metabolite indole-3-propionic acid (IPA). This work...

Ai Ing Lim @AiingLim Mar 24

👶Another elegant study from @babiesresearch on babies vulnerability to infection! A beautiful reminder of the protective role of maternal antibodies, your work continues to inspire us!!

Sing Sing Way @babiesresearch Mar 11

Another twist to why babies more vulnerable to infection. Beyond immune cell immaturity, layering, active suppression... maternal pathogen-targeted antibodies still protect. Grateful @Nature for sharing this glass half-full perspective nature.com/articles/s4158…
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