Ali Arafa

@aliarafaa

Passionate about GU Oncology | Royal College of Surgeons alumnus | Interested in proteogenomics and liquid biopsies 🇪🇬🇺🇸

MN Joined January 2011

530 Following 456 Followers 145 Posts

Latest posts 5

Ali Arafa @aliarafaa Oct 19

Thank you, @EAntonarakis ! Truly honored and grateful to @PCF_Science and the Milken Family Foundation. Thank you for your mentorship, alongside Justin Hwang and @DrJustinDrake , and to the patients who make this work possible. Excited for what's ahead! @UMNCancer

Emmanuel Antonarakis @EAntonarakis Oct 18

Congrats to our newest PCF Young Investigator from Minnesota, the one-and-only Dr. Ali Arafa @aliarafaa. @UMNCancer @UMNews @ThePCCTC @PCF_Science

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Ali Arafa @aliarafaa Apr 20

We profiled extracellular vesicles in plasma and identified proteins associated with treatment outcomes in men with advanced prostate cancer treated with 177Lu-PSMA-617. This work would not have been possible without the mentorship and guidance of @EAntonarakis @DrJustinDrake

Emmanuel Antonarakis @EAntonarakis Apr 20

Congrats @aliarafaa and @DrJustinDrake for your elegant work on plasma extracellular vesicle (EV) proteomics in Pluvicto-treated prostate cancer patients. Blood-based detection of PSMA, B7-H3, STEAP1 and Trop2 will help precision therapeutics! @UMNCancer cell.com/cell-reports-m…

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Ali Arafa @aliarafaa Jun 21, 2025

Excited to share our prostate cancer proteomics work, initially presented at #ASCO25, is now featured on @VuMedi! Grateful for the chance to share how liquid biopsy biomarkers may help shape the future of personalized therapy. @UMNCancer @MPaT_PHCL_UMN

vumedi.com/video/ascor-20…

www.vumedi.com ASCO® 2025 Insights: Liquid Biopsy Approaches to Detect PSMA and 177Lu-PSMA-617 Response in mCRPC A video from Ali Arafa (as part of 2025 ASCO® Annual Meeting Insights Hub), posted on Jun 20, 2025.

Ali Arafa @aliarafaa Jun 4, 2025

@EAntonarakis @DrJustinDrake Incredibly grateful for your mentorship throughout this journey. Huge thanks as well to Dr. Justin Hwang. Building this proteomic assay took a tremendous amount of work, but I’m proud of what we’ve accomplished together. #ASCO25

Emmanuel Antonarakis @EAntonarakis Jun 3, 2025

Congratulations @aliarafaa on developing the first prognostic blood-based PROTEOMIC biomarker for 177Lu-PSMA-617 efficacy, presented at ASCO ‘25. @UMNCancer @UMNews meetings.asco.org/abstracts-pres…

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Ali Arafa @aliarafaa Feb 28, 2025

ATM mutated tumors lack TP53 mutations, while gBRCA1-mutated tumors were enriched for TP53, suggesting synthetic essentiality. ATM-dependent cancers rely on intact TP53, opening new therapeutic vulnerabilities. Disrupting TP53 or inhibiting ATM could unlock targeted treatments!🚀

Emmanuel Antonarakis @EAntonarakis Feb 28, 2025

Largest study of BRCA-associated cancers (24,309) shows that somatic tumor landscape is influenced by germline HRR muts: gBRCA1-altered cancers are enriched in somatic TP53 muts; gATM-altered cancers are depleted in TP53 mut. Congrats @aliarafaa @umncancer aacrjournals.org/clincancerres/…

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