Twitxy
Saved
@anton_gh's profile picture
View on X

Anton Henssen

@anton_gh

Head of preclinical pediatric cancer research @ChariteBerlin ECRC @MDC_Berlin. Extrachromosomal DNA (ecDNA) in cancer. Cancer Grand Challenges Team eDyNAmiC
Berlin, Allemagne Henssenlab.de Joined December 2011
1.5K Following 1.1K Followers 1.5K Posts

Latest posts 5

Pinned post

Anton Henssen @anton_gh
Glad to see this work led by @_YiBei online @CD_AACR 🔥🔥!
Thank you to all the co-authors (esp. Jan Dörr) and @imsmd for the great editorial guidance !!👇🏻👇🏻
Elizabeth McKenna @ElizSMcKenna Jan 11, 2024
Now online in @CD_AACR: Passenger Gene Co-Amplifications Create Collateral Therapeutic Vulnerabilities in Cancer - by @_YiBei,
@anton_gh, Jan Dörr, and colleagues doi.org/10.1158/2159-8… @DKTK_ @ChariteBerlin @MDC_Berlin @berlinnovation
View quoted post on X
7 replies 9 reposts 49 likes 18K views View on X
Anton Henssen @anton_gh
Happy to share our new study published this week in @NatureGenet 🔥🔥🔥🔥

nature.com/articles/s4158…
www.nature.com Micronuclear ecDNA constrains tumor cell fitness and is associated with favorable patient survival Nature Genetics - Single-micronucleus sequencing and live-cell imaging of cancer cells, as well as analyses of biopsies from patients with neuroblastoma, reveal that ecDNA in micronuclei limits...
3 replies 14 reposts 52 likes 4.5K views View on X
Anton Henssen @anton_gh
Very happy to share our new Perspective in Nature Reviews Genetics, led and written primarily by my colleague Liam P. Shaw:

“The shared evolutionary capacities of plasmids and extrachromosomal DNA”

nature.com/articles/s4157…
www.nature.com The shared evolutionary capacities of plasmids and extrachromosomal DNA Nature Reviews Genetics - Plasmids in bacteria and extrachromosomal DNA in cancer both generate copy-number variation, alter gene expression and promote rapid adaptation. In this Perspective, Shaw...
0 replies 4 reposts 7 likes 1.3K views View on X