Pinned post
The B-Lab in Summer 2025 at the Ether Dome @MassGeneral @harvardmed
#science #radonc #radiopharmaceuticals #medphys #biomedeng
#science #radonc #radiopharmaceuticals #medphys #biomedeng
Bertolet Lab / b-lab
@bertoletlab
Lab for RadBio Modeling and Dosimetry for Radiopharmaceutical Therapy at Mass General Hospital & Harvard Medical School
76 Following 120 Followers 129 Posts
Latest posts 5
bertoletlab.mgh.harvard.edu Bertolet Lab Welcomes New Postdocs, Lab Technician, and Visiting Researcher – Bertolet Lab We've grown this fall, so we owe a proper introduction, and a thank-you, to everyone involved. Bobby Dawson joined as a Postdoctoral Research Fellow in the Depa New in @JCO_ASCO (doi.org/10.1200/JCO-26…): we traced where the three numbers that shape almost every radiopharmaceutical therapy trial actually came from. 23 Gy to the kidney, 2 Gy to the marrow, 200 mCi per cycle. None came from the drugs they now limit. A thread.
ascopubs.org Are Radiopharmaceutical Therapy Trials Designed to Undertreat? New paper: liver radioembolization is scored by one number, the average dose. But microspheres lodge in vessels too small for CT to see, so the real dose pattern can vary 5-fold even when that average looks identical. bertoletlab.mgh.harvard.edu/patient-specif…
PAPER: iopscience.iop.org/article/10.108…
PAPER: iopscience.iop.org/article/10.108…
bertoletlab.mgh.harvard.edu New Paper in Physics in Medicine and Biology: Why Mean Dose Doesn’t Tell the Whole Story in Liver... A new patient-specific vasculature framework shows why the mean radiation dose in liver radioembolization can hide very different dose patterns inside the tissu