Semir Beyaz (@beyazlab)

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Our new paper in @NatImmunol explores this question through PPARδ, a lipid-sensing transcription factor that we identify as a regulator of the #fitness balance between #cancer and #immune cells. You can read the open access paper here: nature.com/articles/s4159…

www.nature.com Compartment-specific PPARδ activity controls the outcome of cancer–immune cell competition and... Nature Immunology - Cancer cells and immune cells compete for metabolic fitness within the tumor microenvironment. Here the authors show that PPARδ is instrumental in this battle and that...

Semir Beyaz @beyazlab 5d

Nice picture! Check out our paper for more: nature.com/articles/s4159…

www.nature.com Compartment-specific PPARδ activity controls the outcome of cancer–immune cell competition and... Nature Immunology - Cancer cells and immune cells compete for metabolic fitness within the tumor microenvironment. Here the authors show that PPARδ is instrumental in this battle and that...

Biomedical Picture of the Day BPoD @BPoD_s 5d

Boosting CAR-T therapy to overcome cancer-induced resistance by ramping up PPARδ metabolism factor

📷 Paul Bunk, Ilgin Ergin, Timothy Maher & Vyom Shah et al @beyazlab @CSHL in @NatImmunol
➡️ bpod.org.uk/archive/2026/1… with @rooph

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Semir Beyaz @beyazlab Oct 18

What makes a power #good or #evil? Questions of power, purpose, and restraint run through ancient philosophy and modern storytelling. In #StarWars, the #Force can serve the light or the #darkside. Even those fighting for good can lose control of the power they wield.

Semir Beyaz @beyazlab Apr 26, 2024

Please share! We are looking for an experienced scientist to join our team @CSHL! This exciting project is in collaboration with a leading US-based venture capital firm and biotech company. Apply here: nature.com/naturecareers/…

www.nature.com Research Investigator - Beyaz Lab - Cold Spring Harbor, New York Cold Spring Harbor Laboratory (CSHL) invites applications for a Research Investigator in the laboratory of Dr. Semir Beyaz.

Semir Beyaz @beyazlab Apr 11, 2024

For my friends who don’t want to age, we made something for you: CAR T cells that remove senescent cells in old mice promote stem cell regeneration and tissue fitness in the intestine! Check out our preprint ⬇️

Corina Amor MD, PhD @corina_amor_MD Mar 27, 2024

Happy to share our latest preprint in which we uncovered the potential of senolytic CAR T cells to promote tissue regeneration! Wonderful collaboration with @beyazlab @amor_lab #Senescence #CART #Regeneration.
biorxiv.org/content/10.110…
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Semir Beyaz

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