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We offer an individual-level interpretation of polygenic score (PGS) transferability across genetic ancestries:
PGS accuracy varies individual-to-individual across the genetic-ancestry continuum, even in populations usually labeled as homogeneous.
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nature.com/articles/s4158…
PGS accuracy varies individual-to-individual across the genetic-ancestry continuum, even in populations usually labeled as homogeneous.
1/
nature.com/articles/s4158…
www.nature.com Polygenic scoring accuracy varies across the genetic ancestry continuum Nature - Using two large biobank datasets, a study shows that the accuracy of polygenic scores decreases as a function of relatedness at the individual level when modelling genetic ancestry as a... 
