James Briscoe

@briscoejames

Developmental Biologist working @TheCrick
Neural tube, morphogens & transcriptional networks. Editor-in-chief @Dev_journal
Also @jamesbriscoe@biologists.social

London briscoelab.org Joined March 2010

398 Following 9.8K Followers 6.2K Posts

Latest posts 5

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James Briscoe @briscoejames Apr 22, 2024

Our latest: The cis regulatory logic of temporal & spatial patterning of the vertebrate neural tube

Thread from @joadelas

biorxiv.org/content/10.110…

www.biorxiv.org The cis-regulatory logic integrating spatial and temporal patterning in the vertebrate neural tube The vertebrate neural tube generates a large diversity of molecularly and functionally distinct neurons and glia from a small progenitor pool. While the role of spatial patterning in organising cell...

Joaquina Delas @joadelas Apr 19, 2024

Our latest from @briscoejames lab: How temporal & spatial pattering cues are integrated in the vertebrate neural tube to organise cell type generation during development.

biorxiv.org/content/10.110…

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James Briscoe @briscoejames Aug 5, 2024

Latest on the role of protein turnover in species specific developmental tempo

biorxiv.org/content/10.110…

For a summary of the findings, check the thread by @t_rayon ...

www.biorxiv.org Protein degradation shapes developmental tempo in mouse and human neural progenitors The speed of embryonic development varies considerably between mammalian species, yet the underlying molecular mechanisms remain poorly understood. To investigate the basis for species-specific...

Teresa Rayon @t_rayon Aug 2, 2024

1st #prerpint from the lab together with @briscoejames!

biorxiv.org/content/10.110…

Collaborative effort led by @SNakanoh & Despina Stamataki, with contributions from @enabel_sp, @azziChiA, Alex Pokhilko, and help from proteomics (Crick & BI) + bioinformatic teams 🥂

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James Briscoe @briscoejames Jul 30, 2024

Looking to catch up with dev bio that you might have missed in the past few months?

Start with #InPrePrints from @Dev_journal - summaries of preprints that have caught the eye of experts in the field

journals.biologists.com/dev/collection…

James Briscoe @briscoejames Jul 10, 2024

Highly recommend this by @Pselaphinae on the evolutionary origins of organs

Proposes a framework for division of labour and subfunctionalisation for evolving organs

Insightful, synthetic, & well written. Important implications for the single cell field

annualreviews.org/content/journa…

www.annualreviews.org Organ Evolution: Emergence of Multicellular Function Instances of multicellularity across the tree of life have fostered the evolution of complex organs composed of distinct cell types that cooperate, producing emergent biological functions. How organs...

James Briscoe @briscoejames Jul 10, 2024

Congratulations to Edith and fantastic news for @TheCrick. We're looking forward to welcoming the @heard_lab to London.

The Francis Crick Institute @TheCrick Jul 9, 2024

We are delighted to announce that Professor Edith Heard has been appointed as our new director and chief executive!

Edith, who is currently director-general at @EMBL, will succeed Paul Nurse in leading the Crick from the summer of 2025.

🔗 crick.ac.uk/news/2024-07-0…

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