Bret Scher, MD

Why do so many people believe a keto diet causes heart disease when there’s actually no evidence for that? I explore that in my latest Metabolic Mind video!

The T-REx trial just published in Nature Medicine. It’s a 40-week RCT testing resistance exercise plus tirzepatide.

The findings make complete physiological sense. They also highlight a concern in how we think about lean mass preservation on GLP-1 therapy. 🧵

For those who know @lilyjohnstonmd, you already know her intellect, her balanced discussions, and her passion for metabolic health. But now with her newly published book, we learn so much more about her journey of becoming a surgeon and the toll it took on her life and identity. You don't have to work in medicine to appreciate it and resonate with her journey of chasing a dream only to get it and realize maybe she was chasing the wrong thing all along. I highly recommend her book Disconnected!
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The conclusion from the new STREAM trial in the New England Journal of Medicine says that stopping statins in older adults is "noninferior" to continuing them.

That’s getting lots of attention from supporters and critics. Let's look at what the paper really shows. 🧵

Two patients. Same BMI. One is metabolically healthy. The other has insulin resistance, liver fat, and is on a path toward serious health complications.

A new review in Nature Medicine just detailed this situation and emphasized how treating both of them the same way may not be right. 🧵