Calin Plesa

@calinplesa

Assistant Prof. @UOKnightCampus. Cofounder @SynPlexityDNA.
Protein engineering, gene synthesis, synbio, nanopores, multiplex assays. Opinions my own.

Eugene plesalab.org Joined March 2012

1.9K Following 1.3K Followers 838 Posts

Latest posts 5

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Calin Plesa @calinplesa Mar 3

New lab preprint: if ML struggles with extrapolation, let's expand the diversity of training data with gene synth, DNA shuffling, and ML gen.... also lots of #FluorescentProteins #ProteinEngineering #MachineLearning #SyntheticBiology 1/n

bioRxiv Synthetic Biology @bioRxiv_synbio Mar 3

High Diversity Gene Libraries Facilitate Machine Learning Guided Exploration of Fluorescent Protein Sequence Space biorxiv.org/content/10.648… #biorxiv_synbio
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Calin Plesa @calinplesa Oct 30

Incredibly proud of our small team, with just 30 months from incorporation to acquisition! So much hard work and creativity went into getting here. Super excited to join the GENEWIZ team and scale what we’ve built. Lots more to come!

SynPlexityDNA @SynPlexityDNA Oct 30

SynPlexity is now part of @AzentaSciences! Thrilled to join forces and scale our gene library technology through @GENEWIZSciences to help more scientists build and test at scale.

investors.azenta.com/2026-10-30-Aze…
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Calin Plesa @calinplesa Oct 19

We have two faculty positions open in synthetic biology (one experimental and one computational), both very broadly defined. Deadline is Oct 31. The Dept of Bioengineering in the Knight Campus at UOregon is a great place to work. Come join us! Link below.

Calin Plesa @calinplesa Aug 5

Cool preprint. Rather than engineering TdT around reversible terminators, they use the natural sugar specificity of an RNA polymerase to achieve terminator-free, template-free single-nucleotide addition...

Calin Plesa @calinplesa Jun 15

Looking for a synthetic biology faculty position? Come talk to me at SEED 2026 about upcoming opportunities at
@UOKnightCampus
#synbio #SEED