Pinned post
1/ Spotlight on our former trainee @ryangrui, a physician-scientist and Assist. Prof. at @bcmhouston and @TexasChildrens, focused on childhood immunodeficiencies and immune dysregulation and their genetic and immunologic basis.
Casanova Lab
@casanova_lab
We're a research lab at UT Southwestern (Texas) and Necker Hospital (Paris) studying human genetic and immunological determinants of infectious diseases.
519 Following 10K Followers 6.5K Posts
Latest posts 5
This is a very important study that characterizes in great depth the B cell basis of auto-Abs neutralizing type I IFNs:
Cellular origin and characterization of autoantibodies against type I IFNs in COVID-19 and APS-1 rupress.org/jem/article/22…
Cellular origin and characterization of autoantibodies against type I IFNs in COVID-19 and APS-1 rupress.org/jem/article/22…
rupress.org Cellular origin and characterization of autoantibodies against type I IFNs in COVID-19 and APS-1 Sun et al. investigate the cellular origins, B cell states, and functional properties of type I IFN–neutralizing autoantibodies associated with severe COVI A superb study !
New paper from us 😊 rupress.org/jem/article/22…View quoted post on X
Type I IFN autoantibodies in three of seven Europeans with life-threatening Usutu virus infection rupress.org/jhi/article/3/…
rupress.org Type I IFN autoantibodies in three of seven Europeans with life-threatening Usutu virus infection We report autoantibodies neutralizing type I IFNs in three of seven European patients with severe Usutu virus infection. The patients are males and aged 43 MHC-II deficiency in a large Algerian cohort: Clinical, immunological, and genetic characterization rupress.org/jhi/article/3/…
rupress.org MHC-II deficiency in a large Algerian cohort: Clinical, immunological, and genetic characterization This study characterizes the clinical, immunological, and genetic spectrum of MHC-II deficiency in the largest cohort reported to date. It identifies recur