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Our October issue is now live!
Get ‘wrapped’ up in this month’s exciting microbiology.
cell.com/cell-host-micr…
Get ‘wrapped’ up in this month’s exciting microbiology.
cell.com/cell-host-micr…
Cell Host & Microbe
@cellhostmicrobe
The scientific editors of Cell Host & Microbe, a Cell Press journal, bring you the latest information and insights from the forefront of host-microbe research.
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Latest posts 5
Microbial-derived methotrexate metabolite alleviates inflammation
Gut microbial metabolism of methotrexate generates DAMPA. DAMPA acts through STAT3 to promote mitochondrial function and protect against inflammation in context of IBD.
cell.com/cell-host-micr…
Gut microbial metabolism of methotrexate generates DAMPA. DAMPA acts through STAT3 to promote mitochondrial function and protect against inflammation in context of IBD.
cell.com/cell-host-micr…
Weekend revisit: Probiotics eradicate glioblastoma
E. coli Nissle produces bispecific engagers to recruit & instruct in situ-edited CAR macrophages. Microbe-guided CAR macrophages overcome glioblastoma antigenic heterogeneity & establish antitumor memory
cell.com/cell-host-micr…
E. coli Nissle produces bispecific engagers to recruit & instruct in situ-edited CAR macrophages. Microbe-guided CAR macrophages overcome glioblastoma antigenic heterogeneity & establish antitumor memory
cell.com/cell-host-micr…
www.cell.com Engineered probiotics recruit CAR macrophages and establish immune memory to eradicate heterogene... Zhang et al. report a synthetic host-microbe immune circuit in which probiotics locally produce bispecific engagers to recruit and instruct in situ-edited CAR macrophages. Macrophage-microbe crosst... Hot paper revisit 🔥
lncRNA induces trained immunity against TB
Exosomal lncRNA TRCR1 derived from Mtb resisters induces trained immunity via CLOCK-mediated epigenetic reprogramming. Mycobacteria induces TRCR1+ exosomes, boosting immunity & BCG efficacy
cell.com/cell-host-micr…
lncRNA induces trained immunity against TB
Exosomal lncRNA TRCR1 derived from Mtb resisters induces trained immunity via CLOCK-mediated epigenetic reprogramming. Mycobacteria induces TRCR1+ exosomes, boosting immunity & BCG efficacy
cell.com/cell-host-micr…
www.cell.com A CLOCK-targeting lncRNA induces trained immunity against tuberculosis Yu et al. discover that TRCR1, a tuberculosis resister-derived exosomal lncRNA, induces trained immunity via CLOCK-mediated epigenetic reprogramming. They show that mycobacterial protein MPT53... Microbial products trigger chemosensory dialogues via GPCRs
Libraries of gut metabolites+GPCR-seq reveal how gut senses environmental chemicals. ID microbial products activating specific receptors, including those triggering serotonin or linking to IBD
cell.com/cell-host-micr…
Libraries of gut metabolites+GPCR-seq reveal how gut senses environmental chemicals. ID microbial products activating specific receptors, including those triggering serotonin or linking to IBD
cell.com/cell-host-micr…
